Results 51 to 60 of about 5,802,922 (308)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Lost Experience : Statuts d’Emerson dans la série Lost

open access: yesTV Series, 2018
Lost is a polysemic show which mobilizes, for that purpose, the trope of homonymy. Many characters go by the name of great historical figures. This process questions the theme of utopia and ideal society.
Guillaume Dulong
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Comparing Acoustic Tag Attachments Designed for Mobile Tracking of Hatchling Sea Turtles

open access: yesFrontiers in Marine Science, 2017
The poorly understood movements of sea turtles during the “lost years” of their early life history have been characterized as a “passive drifter” stage. Biologging technology allows us to study patterns of dispersal, but the small body size of young life
Aimee L. Hoover   +5 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Co-production in the Lost Mothers Project: transforming criminal justice narratives through Lived experience engagement

open access: yesResearch Involvement and Engagement
The Lost Mothers Project researches the repercussions of mandatory separation between newborns and women in the Criminal Justice System (CJS), aiming to address gaps in evidence and decision-making for pregnant women within the CJS.
Laura Abbott   +2 more
doaj   +1 more source

Experimental Study, Characterization and Application of Starch-Graft-Acrylamide Gel for Plugging

open access: yesMedžiagotyra, 2018
During underbalance drilling, completion and workover wells, plugging channeling, blocking preformation and plugging formation water are inevitable problems. Gel is one of the most effective and convenient method to solve the problem.
Zhen LI   +6 more
doaj   +1 more source

LOST IS FOUND

open access: yesArt/Research International, 2020
The tenure track is a contentious space in which pre-tenure faculty are asked to navigate the corporatization of the university, and uncertainty with regards to the expectations of success to achieve tenure.
Samantha T. Nolte-Yupari, Joana Hyatt
doaj   +1 more source

In search of lost introns

open access: yes, 2007
Many fundamental questions concerning the emergence and subsequent evolution of eukaryotic exon-intron organization are still unsettled. Genome-scale comparative studies, which can shed light on crucial aspects of eukaryotic evolution, require adequate ...
Adachi   +53 more
core   +1 more source

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