Results 71 to 80 of about 5,808,650 (308)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Design Deficiencies and Lost Votes [PDF]
, 2011 In 2010, tens of thousands of votes in New York did not count due to overvotes -- the invalid selection of more than one candidate. This report demonstrates how the lack of adequate overvote protections disproportionately affected the state's poorest ...
Lawrence Norden, Sundeep Iyer
core
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Неврология, нейропсихиатрия, психосоматика, 2010 Physicians have been found to be inadequately aware of the structure of the causes of headache, vertigo, and their clinical importance in patients with essential hypertension. Incorrect ideas lead to the unfounded application of diagnostic techniques for
A. E. Manoylov
doaj +1 more source
Shakespeare\u27s Lost Palindrome [PDF]
, 1976 In the summer of 1973, Miss O. P. Helier, a Yorkshire antiquarian, spent a few happy days rummaging through antiques shops in London. Among the items she unearthed was a small metal box with a label that read: Ashes from ye gret London fyre, 1666 .
Fanning, James
core +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Reconstructing the image of the ideal city in Renaissance painting and theatre: Its influence in specific urban environments. Digital technology and visual culture [PDF]
, 2016 This paper shows a virtual reconstruction based on a comparative study between scenography designs of urban views, and similar landscapes used in painting, in order to eventually find correspondences with specific urban environments.Universidad de Málaga.
Gonzalez-Roman, Maria del Carmen +1 more
core
The burden of premature mortality in Poland analysed with the use of standard expected years of life lost [PDF]
, 2015 Background: Despite positive changes in the health of the population of Poland, compared to the EU average, the average life expectancy in 2011 was 5 years shorter for males and 2.2 years shorter for females.
Bryła, Marek +3 more
core +2 more sources
Current Biology, 2009 SummaryThe world faces losing hundreds of languages according to a new Unesco atlas, writes Nigel Williams.
openaire +2 more sources
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source