Results 51 to 60 of about 1,405,729 (293)

Formulation Design of Drilling Fluid Loss Control and Plugging Strategies in Deepwater Subsalt Reservoirs

Zuanjingye yu wanjingye
Subsalt oil and gas resources are abundant worldwide, with significant reserves located in the deepwater offshore regions of Brazil. The Mero field is a typical example of deepwater subsalt oil and gas resources, located in the southeastern Santos Basin ...
Chengyuan XU, Jiangcheng ZHONG, Haifeng ZHU, Ming XIANG, Zhiqiang LIN, Jie YANG, Jiaxu CHEN   +6 more
doaj   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Engineered Fiber Based Lost Circulation Pill to Abridge Lost Circulation of Geothermal Well

Journal of Earth Energy Science, Engineering, and Technology, 2018
Loss circulation is a major problem and known as the biggest challenge during drilling and well construction.This can leadsto various consequences,such as stuck pipe, loss of material and time to combat the losses, and even losing the well itself. Severe loss circulation conditions are often met while drilling geothermal wells in Indonesia.
Apriyansah Toni, Astra Agus Pramana, Bambang Kustono   +2 more
openaire   +2 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Machine learning-based diagnosis of fracture-induced lost circulation and intelligent selection of lost circulation control fluids

Meitian dizhi yu kantan
Objective and Method Drilling operations in the Changqing area face several challenges in lost circulation, including complex types, significantly different characteristics, and difficulty in designing plugging formulations. To address these issues, this
Huan SUN, Mingming ZHU, Jinshu WANG, Lu YAO, Fangfang ZHOU, Xuebin TAN, Yan SUN, Yanping QU, Ning CHEN   +8 more
doaj   +1 more source

Ethical Foreground and Background in Adult Educator Work

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Adult educators work in a complex ethical environment. The very act of contributing to the learning of another is fraught with moral overtones. In this paper we consider the ethical dimensions of adult educator practice by distinguishing the ethical features of the context or ‘background’ of practice from the ethical capabilities and decision ...
Steven Hodge, Sonal Nakar
wiley   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

Lost Circulation Prediction Based on Long Short-Term Memory Network and Random Forest Algorithm

Zuanjingye yu wanjingye
Lost circulation is one of the key factors restricting drilling safety and efficiency. To realize accurate prediction of lost circulation, a hybrid model for the prediction of lost circulation is presented based on long short-term memory (LSTM) and ...
Aiting CAI, Junlin SU, Kun DAI, Han ZHAO, Jiayi WANG   +4 more
doaj   +1 more source

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali, Priyanka Menon, Halil I. Corbali, Ram Jagannathan, Allan I. Levey   +4 more
wiley   +1 more source

Research on heat transfer law of multiphase flow in wellbore under coexistence of overflow and lost circulation in deepwater drilling

Case Studies in Thermal Engineering
A reliable and accurate wellbore heat transfer model is essential for making critical decisions during deepwater drilling operations. This study develops a transient coupled flow model for the coexistence of overflow and lost circulation simulation in ...
Xin Yu, Yonghai Gao, Xinxin Zhao, Hongxing Yuan, Luxiang Liu, Baojiang Sun   +5 more
doaj   +1 more source