Results 151 to 160 of about 13,605 (301)

Observation of Magnetic‐Anisotropy Crossover and High‐Temperature Skyrmions in the Dirac Magnet Fe3Ge with a Distorted Kagome Lattice

open access: yesAdvanced Science, EarlyView.
A temperature‐driven magnetic anisotropy crossover is revealed in the Dirac kagome magnet Fe3Ge with a distorted kagome lattice. The transition from easy‐plane to easy‐axis magnetic anisotropy stabilizes robust Bloch‐type skyrmions over an exceptionally wide temperature window of 375–650 K.
Yalei Huang   +15 more
wiley   +1 more source

Legionella Becoming a Mutualist: Adaptive Processes Shaping the Genome of Symbiont in the Louse Polyplax serrata

open access: yes, 2017
Genomic modifications coupled with the first known transition of a Legionella bacterium to symbiosis with insects (louse Polyplax serrata). Apart from characteristics typical for other obligatory symbionts in insect (genome reduction), the main ...
ŘÍHOVÁ, Jana
core  

Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy

open access: yesAdvanced Science, EarlyView.
Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song   +7 more
wiley   +1 more source

Device for destroying pea louse, undated

open access: yes
Photo of three men pulling a device in a field. Caption: "Device for destroying pea louse.

core  

An Engineered HR1‐Stem Helix‐HR2 Trimeric Platform for Developing Broad‐Spectrum Coronavirus Vaccines

open access: yesAdvanced Science, EarlyView.
Sun et al. report a self‐assembling trimeric subunit vaccine platform termed RHS, which integrates the JN.1 receptor‐binding domain (RBD) with the heptad repeat 1 (HR1), stem helix (SH), and heptad repeat 2 (HR2) regions. The SARS‐CoV‐2 RHS vaccine elicits variant‐reactive RBD‐specific antibodies and cross‐reactive SH‐specific antibodies against ...
Xikui Sun   +18 more
wiley   +1 more source

The Effect of Ligand Reactivity and Carrier Mechanics on Thiol‐Mediated Cellular Uptake for miRNA Nano‐Drugs

open access: yesAdvanced Science, EarlyView.
The effect of ligand reactivity and carrier mechanics on thiol‐mediated uptake was investigated at the single‐molecule/particle level. The interaction kinetics of LA and AspA with membrane thiols were quantified; AspA is more efficient due to the higher binding affinity, greater binding stability, and more double‐disulfide binding, as well as greater ...
Zhuang Zhang   +7 more
wiley   +1 more source

Human Lice: Body Louse, Pediculus humanus humanus Linnaeus and Head Louse, Pediculus humanus capitis De Geer (Insecta: Phthiraptera (Anoplura): Pediculidae)

open access: yes, 2002
This document is EENY-104, one of a series of the Entomology and Nematology Department, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida. Original publication date July 1999.
H. V. Weems, Jr., Thomas R. Fasulo
core  

Symbiont‐Induced HSP83 Establishes Two‐Tiered Control of Antifungal Immunity in an Invasive Beetle–Fungus Complex

open access: yesAdvanced Science, EarlyView.
In an invasive beetle–fungus complex, the mutualist Leptographium procerum induces host HSP83 and modulates Toll‐dependent antifungal immunity. HSP83 mediates two‐tiered control by associating with selected fungal recognition receptors and restraining Dorsal‐driven antimicrobial peptide transcription.
Qingtai Yang   +8 more
wiley   +1 more source

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

open access: yesAdvanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li   +11 more
wiley   +1 more source

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