American Journal of Botany, EarlyView.Abstract Premise Recent advances in genomic technologies now enable the reconstruction of evolutionary histories at fine spatial scales, illuminating the complex dynamics that shape biodiversity patterns in naturally discontinuous, archipelago‐like ecosystems such as cloud forests.
Leopoldo Hurtado‐Reveles +4 more
wiley +1 more source
Site‐Specific Protein Bioconjugation Through Cellular Incorporation of Noncanonical Amino Acids
Angewandte Chemie, EarlyView.Genetic code expansion (GCE) enables site‐specific installation of noncanonical amino acids containing bioorthogonal conjugation handles, allowing precise, homogeneous protein modification. This review examines the principles of orthogonal translation, surveys the chemistries available for chemoselective labeling, and highlights emerging multi‐site ...
Rahul Sarkar +2 more
wiley +2 more sources
<i>Crataerina melbae</i> louse flies are competent vectors of <i>Trypanosoma</i> sp. associated with nestling mortality in Alpine swifts (<i>Tachymarptis melba</i>). [PDF]
Int J Parasitol Parasites WildlMoré G +6 more
europepmc +1 more source
American Journal of Botany, EarlyView.Abstract Premise Although the megafossil flora of the upper Albian–lower Cenomanian Dakota Formation in Kansas is well known for angiosperms, monocots have not been reported previously. Methods A mesofossil flower was discovered by X‐ray analysis of a specimen collected more than a century ago from the Dakota Sandstone of central Kansas.
Bruce H. Tiffney +4 more
wiley +1 more source
Molecular Basis of NPY Recognition and Ligand Selectivity at the Neuropeptide Y5 Receptor
Angewandte Chemie, EarlyView.Here, we present the first active structure of the neuropeptide Y5 receptor (NPY5R) in complex with its endogenous ligand NPY and the Gi1 protein. The cryo‐electron microscopy structure, validated by extensive mutagenesis studies, gives important insights into the molecular mechanisms underlying ligand binding and receptor activation.
Lisa Christin Peuker +8 more
wiley +2 more sources
Living within: endosymbiosis in parasites of medical importance-profits, expenses, and implications for host-parasite interactions. [PDF]
Front Cell Infect MicrobiolAbdel Shafi IR +2 more
europepmc +1 more source
American Journal of Industrial Medicine, EarlyView.ABSTRACT Background Exposures to human pathogens and toxins in licensed facilities in Canada have been monitored by a federal surveillance system since 2015, yet the affected persons (APs) in these incidents remain uncharacterized. This study comprehensively describes APs, highlighting sector‐specific patterns and trends over time.
Emily F. Tran +4 more
wiley +1 more source
Insights into the microbiota profile of Pediculus humanus capitis using metagenomic next-generation sequencing and molecular detection of unexpected pathogen DNA in Hunan Province, China. [PDF]
Parasit VectorsFu YT +8 more
europepmc +1 more source
Investigation of avian louse flies as potential vectors of protozoan and bacterial pathogens of veterinary importance. [PDF]
Sci RepKeve G +16 more
europepmc +1 more source
Polyproline: A Synthetic Polypeptide With Unique Properties
Angewandte Chemie, EarlyView.Poly‐L‐proline is a unique polypeptide distinguished by its well‐defined secondary structures and unusual thermal behavior. This mini review highlights recent advances in the synthesis of poly‐L‐proline by N‐carboxyanhydride (NCA) polymerization, the formation of structurally defined architectures and nanostructures, and emerging strategies that ...
Rosanna Le Scouarnec +3 more
wiley +1 more source