Results 91 to 100 of about 317,672 (284)
Ankara Üniversitesi Dil ve Tarih-Coğrafya Fakültesi Dergisi, 2017 This article applies one aspect of Jean-Paul Sartre’s existentialist approach as found in his philosophic masterpiece Being and Nothingness to a particularly prevelant pair of characters in classical Near Eastern poetry.
Fatma DORE
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Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Los celos en Proust y Shakespeare: un caso de voyeurismo narrativo
Anuario de Letras Modernas, 2009 Voyeurism is often the mise en scene the jealous man builds in his imagination both to goad and relish in his anguish at the thought of his/her beloved being possessed by the rival—real or imaginary.
Luz Aurora Pimentel
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, 1982 Into the arena of everyday life the Living Christ invades. Loving, wooing, calling us to himself, He pursues us each- as the Lover seeks His beloved- until all our attempts to find meaning, love, peace, culminate in our being found by ...
Anderson, Paul
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Tancerz i szachista w świecie słów
Między Oryginałem a PrzekłademDANCER AND CHESS PLAYER IN A WORLD OF WORDS This article is devoted to Andrzej Lewandowski, a translator from Toruń born in 1937, a doctor of mathematics, an outstanding chess player, and a lover of Italy, music, and mountains, among other things.
Monika Krajewska
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Preference for Information and Dynamic Consistency [PDF]
We provide necessary and sufficient conditions for a dynamically consistent agent always to prefer more informative signals (in single-agent problems). These conditions do not imply recursivity, reduction or independence.
Atsushi Kajii, Ben Polak, Simon Grant
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