Results 71 to 80 of about 319,004 (304)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
A of Political-Social Discourse Analysis of the Relationship between Lover and Beloved onein the lyric poems of Sa’di [PDF]
متن شناسی ادب فارسی, 2017 In romantic literature of Iraqi style, particularly in Sa’di’s lyric poems, the cruelty and oppression of the sweetheart and the degradation and contempt of the lover in front of her are proposed abundantly.
Alli Akbar Bagheri Khalili +1 more
doaj
Keakuratan Terjemahan Gaya Bahasa pada Novel Lady Chatterley’s Lover
Ranah: Jurnal Kajian Bahasa, 2018 Translating accuracy of source language into target language in a literary work require high appropriatness that retain the beauty of the language. The purpose of this study is to identify and describe level of accuracy of the translation in the figure ...
Nidya Pratiwi, M.R Nababan, NFN Djatmika
doaj +1 more source
Common Currency, Common Market? [PDF]
Does the common currency promote goods market integration within the EMU? We argue that such an effect is likely, but that the mechanism typically proposed – lover costs of arbitrage because of increased price transparency – is likely to be of minor ...
Richard Friberg
core
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
InterAlia, 2008 Based on a presentation delivered at the Parameters of Desire conference in Bielsko-Biala, Poland, June 8-11, 2003, "If Queer Theory Were My Lover” attempts to examine the role of queer theory in the academy using a multi-genre-or trans-genre-format ...
Nathan Long
doaj +1 more source
The "lover" and early modern fandom
Transformative Works and Cultures, 2011 A look at 17th century fannish practices through the works of "lovers" (or "amateurs") who primarily focussed on ideas, practices, and entities rather than individuals.
Vera Keller
doaj +1 more source
Mme de Graffigny’s story [PDF]
, 2004 This article argues that Graffigny's "Lettres d'une Péruvienne" and "Cénie" tell essentially the same story, that of a woman sundered from her high estate and her betrothed.
Howells, Robin
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source