Results 61 to 70 of about 34,469 (248)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Samuel Lover, 1797-1868, Irish painter, illustrator, novelist, and ...
Benatti, Francesca
core +5 more sources
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
“The country of his past”: Homecoming in “A Modern Lover” and “The Shades of Spring”
In the two early stories, “A Modern Lover” and “The Shades of Spring,” Lawrence imagines an autobiographical figure returning to his home country to renew connection with the young woman he had loved (a version of Jessie Chambers).
Keith Cushman
doaj +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
For voice and piano.; Caption title.; Engraved.; "Favorite vocal music" -- Cover.; Also available online http://nla.gov.au/nla.mus-an9405080; MUS: N, GE 301/1/6 ...
Lover, Samuel, 1797-1868.
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Based on a presentation delivered at the Parameters of Desire conference in Bielsko-Biala, Poland, June 8-11, 2003, "If Queer Theory Were My Lover” attempts to examine the role of queer theory in the academy using a multi-genre-or trans-genre-format ...
Nathan Long
doaj +1 more source
Good soldier, better politician, charming lover
Caesar: Life of a Colossus Adrian Goldsworthy Phoenix: Yale University Press, 2006 Julius Caesar disregarded warnings about the Ides of March. He believed, as Shakespeare would have us know, that he was more dangerous than danger itself. That precisely
Syed Badrul Ahsan
doaj +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source

