Results 31 to 40 of about 8,998 (265)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The foxes that ruin the vineyards - a literal interpretation of Song of Songs 2:15

open access: yesActa Theologica, 2003
This article focuses on a literal interpretation of Song of Songs 2:15. Initially, this verse is identified as an independent unit, as a song intended to scare off. Now it forms part of a garden/countryside scenery (2:8-17).
S. Fischer
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Opp som en løve og ned som en skinnfell – hvor er departementet?

open access: yesMagma, 2020
Dette nummeret av Magma burde inneholdt en oppdatering av sentrale lover for oss økonomer. De siste årene har vi hatt fire sentrale lover opp til revurdering: aksjeloven, regnskapsloven, regnskapsførerloven og revisorloven.
Finn Kinserdal, Kjell Ove Røsok
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Designing "Meows .Co" Application as a Tool for Cat Lovers

open access: yesInternational Journal of Research and Applied Technology, 2023
Cats are one of the most common pets kept by humans. During a pandemic, keeping cats has many benefits for mental and physical health. The purpose of this research is to design a mobile-based application that functions as a tool for cat lovers who are ...
Albanna Rahmadani S   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Thrasymachus, the Sight-lover

open access: yesRevista de Filosofia Antiga
The aim of this paper is to explain why Thrasymachus, upon first appearing in Republic I, prohibits Socrates from defining justice as what is good. I argue that Thrasymachus views such definitions as equivocal, since he conceives of the good as relative:
Clifford Roberts
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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