Results 141 to 150 of about 302,850 (308)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

A Fiber Optical Sensor For Non-Contact Vibration Measurements [PDF]

open access: yes, 2009
This paper describes an intensity based optical sensor for the evaluation of accelerations from non-contact displacement measurements. Plastic optical fibers are used to collect the reflected light from several points on the vibrating surface, allowing ...
Perrone, Guido   +2 more
core  

Performance characterisation of a new photo-microsensor based sensing head for displacement measurement

open access: yes, 2016
This paper presents a robust displacement sensor with nanometre-scale resolution over a micrometre range. It is composed of low cost commercially available slotted photo-microsensors (SPMs).
Potdar, Akshay Anand   +2 more
core   +1 more source

Early Recognition of Treatment‐Responsive Rapidly Progressive Dementia: The Modified STAM3mP Score

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Early identification of patients with treatment‐responsive rapidly progressive dementia (RPD) is important as early treatment improves outcomes. The STAM3P score identifies treatment‐responsive RPD using “high risk” presenting features. We optimized performance by adding a time component (i.e., dementia within 3 months) and validated the ...
R. W. van Steenhoven   +16 more
wiley   +1 more source

Secure Clustering Protocols in Wireless Sensor Networks

open access: yes, 2016
Wireless sensor networks (WSNs) are poised of huge number of low-cost and tiny devices i.e. senor nodes which communicate over wireless media. Various WSN based projects produced fruitful and interesting results that greatly improves our life.
Sharma, S C, SINGH, SANTAR PAL
core  

A Low-Cost Sensor System Installed in Buses to Monitor Air Quality in Cities. [PDF]

open access: yesInt J Environ Res Public Health, 2023
Correia C   +6 more
europepmc   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Trusted routing for resource-constrained Wireless Sensor Networks

open access: yes, 2010
Designing a reliable and trusted routing scheme for resource-constrained Wireless Sensor Networks (WSNs) is a challenging task due to the lack of infrastructure and the highly dynamic network topology.
Dixon, M.W.   +11 more
core   +1 more source

Assessment of aerosol persistence in ICUs via low-cost sensor network and zonal models. [PDF]

open access: yesSci Rep, 2023
Glenn K   +5 more
europepmc   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi   +17 more
wiley   +1 more source

Home - About - Disclaimer - Privacy