Results 81 to 90 of about 11,568,098 (290)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Vehicle localization with low cost radar sensors

open access: yes2016 IEEE Intelligent Vehicles Symposium (IV), 2016
Autonomous vehicles rely on GPS aided by motion sensors to localize globally within the road network. However, not all driving surfaces have satellite visibility. Therefore, it is important to augment these systems with localization based on environmental sensing such as cameras, lidar and radar in order to increase reliability and robustness.
Erik Ward, John Folkesson
openaire   +4 more sources

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Developing low-cost intelligent wireless sensor networks for aquatic environments

open access: yes, 2010
Aquatic environments are extremely difficult for developing, deploying, and maintaining wireless sensor networks. Networks deployed in aquatic settings face multiple challenges, such as marine fowling of equipment, limited power supply, communications ...
Atkinson, Ian   +20 more
core   +1 more source

The optimisation of a paired emitter-detector diode optical pH sensing device [PDF]

open access: yes, 2010
With recent improvements in wireless sensor network hardware there has been a concurrent push to develop sensors that are suitable in terms of price and performance.
Corcoran, Brian   +11 more
core   +2 more sources

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Energy managed reporting for wireless sensor networks

open access: yes, 2008
In this paper, we propose a technique to extend the network lifetime of a wireless sensor network, whereby each sensor node decides its individual network involvement based on its own energy resources and the information contained in each packet.
Merrett, Geoff V.   +3 more
core   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Low-cost metamaterial-on-paper chemical sensor

open access: yesOptics Express, 2017
We present a disposable low cost paper-based metamaterial for sensing liquids based on their dielectric properties. The sensor is based on resonance shift due to the change in the effective capacitance of each resonator in the metamaterial array. Key novelty in the design is the implementation of metamaterial on low cost and ubiquitous paper substrate.
Aydin, Sadeqi   +2 more
openaire   +2 more sources

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

open access: yesMolecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara   +10 more
wiley   +1 more source

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