Results 171 to 180 of about 281,346 (214)

Discordance between remnant cholesterol and low-density lipoprotein cholesterol predicts incident hypertension: a 9-year prospective cohort study in Chinese adults. [PDF]

BMC Cardiovasc Disord
Wu XF, Ma CF, Zhang YC, Liu S, Yan B, Li XX.   +5 more
europepmc   +1 more source

ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential

iNew Medicine, EarlyView.
ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang, Xinyan Li, Honglu Shi, Gaolei Song, Zhifu Xie, Jingya Li   +5 more
wiley   +1 more source

Elevated low-density lipoprotein cholesterol levels and prostate cancer risk: UK Biobank evidence. [PDF]

World J Urol
Alexa R, Kranz J, Thöne M, Grundl S, Hoffmann M, Koop PH, Feng C, Schneider KM, Schneider C, Saar M.   +9 more
europepmc   +1 more source

Bisphenol A and Its Analogs: Toxicity Analysis in Mouse and Rat Liver—A Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) and its analogs are widely recognized for their use in industry and plastic manufacturing. Consequently, humans and animals are continually exposed to various substances in their daily lives. This review evaluates the hepatic toxicity of BPA and its analogs in mice and rats, with particular emphasis on molecular mechanisms ...
Sevda Bagdatli, Muhammed Canik, Gizem Gencay, Nurbanu Zengin, Tarık Dinc, Nazan Deniz Yön   +5 more
wiley   +1 more source

Cumulative Atherogenic Index of Plasma Burden and Risk of Non-Fatal Myocardial Infarction and Ischemic Stroke Beyond Cumulative Low-Density Lipoprotein Cholesterol Burden. [PDF]

Circ Rep
Inoue N, Kato H, Takahashi N, Ohinata R, Sato Y, Mishina T, Iwata K, Suzuki A, Joko Y, Takayama Y, Miyachi M, Morikawa S.   +11 more
europepmc   +1 more source

Machine Learning–Based Comparative Analysis of Blood Cell–Derived Inflammatory Indices for Predicting MAFLD and Liver Fibrosis: Evidence From NHANES 2017–2020

Journal of Clinical Laboratory Analysis, EarlyView.
This research assesses the correlations and diagnostic efficacy of blood cell‐derived inflammatory indicators in predicting metabolic dysfunction‐associated fatty liver disease (MAFLD) and liver fibrosis using NHANES 2017–2020 data. AISI had the highest predictive capability for MAFLD, while PLR served as the most efficacious indicator for fibrosis ...
Hao Chen, Qinmei Chen, Xiangqian Wang, Yixian He, Xiqiao Zhou   +4 more
wiley   +1 more source

Retraction Note: Association between low density lipoprotein cholesterol levels and prostate cancer risk in non-hypertensive middle-aged and older American men. [PDF]

Sci Rep
Zhou Z, Huang Z, Zhao Y, Wang Y, Niu Y.
europepmc   +1 more source

Study of Risk Factors and Image Findings of Isolated Abdominal Incidentally Detected Aortic Dissection

Journal of Clinical Ultrasound, Volume 53, Issue 3, Page 429-435, March/April 2025.
We detect the risk factors and image characteristics of incidentally detected IAAD. Independent risk factors of IAAD included fatty liver and smoking. In the ultrasound findings of IAAD, an intimal flap was frequently observed. In the CT scan, displacement of intimal calcifications was frequently observed. For suspected IAAD, the abdominal aorta should
Hiromasa Tsubouchi, Hidenori Onishi, Koji Maeno, Masaya Nakagaichi, Ikue Tsukushi, Youichi Kitano, Yoshitaka Makino, Hiroyuki Hayashi, Hidekazu Terasawa, Hiroko Kabuto, Toshihiro Misawa, Taku Sanada, Azusa Hisada, Kazuo Notsumata, Kazuhiro Okafuji, Osamu Yamamura   +15 more
wiley   +1 more source

Lipoprotein(a) Concentration and Achieving Target Values of Low-Density Lipoprotein Cholesterol Calculated by Different Equations. [PDF]

Diseases
Afanasieva OI, Tyurina AV, Klesareva EA, Ezhov MV, Pokrovsky SN.   +4 more
europepmc   +1 more source

Association Between Deep Gray Matter Iron Deposition Dysregulation and Cognitive Performance in Type 2 Diabetes Mellitus Patients: A Quantitative Susceptibility Mapping Study

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Type 2 diabetes (T2DM) heightens cognitive impairment risk, yet the mechanisms remain unclear. Hyperglycemia‐induced iron dysregulation in deep gray matter (DGM) nuclei may be a crucial mechanism. Purpose To investigate DGM iron deposition in T2DM using Quantitative Susceptibility Mapping (QSM) and determine its association with ...
Kun Wang, Jiahe Wang, Ziyu Diao, Xin Tan, Shijun Qiu, Jie An   +5 more
wiley   +1 more source