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A Paradigm Shift in Low Dose Radiation Biology [PDF]

Atom Indonesia, 2015
When ionizing radiation traverses biological material, some energy depositions occur and ionize directly deoxyribonucleic acid (DNA) molecules, the critical target. A classical paradigm in radiobiology is that the deposition of energy in the cell nucleus
Z. Alatas
doaj   +2 more sources

Carcinogenesis induced by low-dose radiation [PDF]

Radiology and Oncology, 2017
Although the effects of high dose radiation on human cells and tissues are relatively well defined, there is no consensus regarding the effects of low and very low radiation doses on the organism.
Piotrowski Igor, Kulcenty Katarzyna, Suchorska Wiktoria Maria, Skrobała Agnieszka, Skórska Małgorzata, Kruszyna-Mochalska Marta, Kowalik Anna, Jackowiak Weronika, Malicki Julian   +8 more
doaj   +3 more sources

Reevaluating the Paradox: Does Low-Dose Radiation from A-Bombs Affect Lifespan and Cancer Mortality? [PDF]

Journal of Biomedical Physics and Engineering
Reevaluating the Paradox: Does Low-Dose Radiation from A-Bombs Affect Lifespan and Cancer Mortality?Reevaluating the Paradox: Does Low-Dose Radiation from A-Bombs Affect Lifespan and Cancer Mortality?Reevaluating the Paradox: Does Low-Dose Radiation from
Razieh Rashidfar, Zeynab Seyedi Sarhad, Seyed Mohammad Javad Mortazavi, Lembit Sihver   +3 more
doaj   +2 more sources

Low-dose radiation research insights in experimental animals: A gateway to therapeutic implications [PDF]

Veterinary World
In recent years, a significant research effort has been underway to explore the effects of low-dose radiation (LDR). Animal models play a key role in various fields of research, including biomedicine, pharmaceutical, environmental, and behavioral studies.
Nayanatara Arunkumar, Megha Gokul, Harini Narayanam, A. K. Ananya   +3 more
doaj   +2 more sources

The impact of long-term low-dose ionizing radiation on human health: risks and protective measures [PDF]

Frontiers in Medicine
PurposeWith the widespread application of ionizing radiation in medicine and other fields, the health impacts of long-term occupational exposure to low-dose ionizing radiation (LDIR) on the human body have garnered growing attention.
Yue Zhang, Rongrong Li, Xiaoling Li, Ru Li, Tiankun Lu, Xiaohu Zhong, Zexuan Li, Haifang Zhang, Junfeng Wang   +8 more
doaj   +2 more sources

Low-dose Pretreatment for Radiation Therapy

Dose-Response, 2010
In radiotherapy, a large radiation dose must be applied to both cancer and neighboring healthy cells. Recent experiments have shown that a low dose of ionizing radiation turns on certain protective mechanisms that allow a cell to better survive a ...
Richard Blankenbecler
doaj   +3 more sources

Case report: Low-dose radiation reverses pembrolizumab resistance in melanoma [PDF]

Frontiers in Oncology
Immunotherapy has been the mainstay of the initial systemic treatment for metastatic melanoma regardless of the tumor’s genetic mutation status (Atkins et al., 2022).
Ka Hey Agnes Fong, Isaac Ho, Tsz Him So
doaj   +2 more sources

PHA stimulation may be useful for FDXR gene expression-based biodosimetry [PDF]

Iranian Journal of Basic Medical Sciences, 2020
Objective(s): Nowadays, ionizing radiation (IR) has a significant contribution to the diagnostic and therapeutic medicine, and following that, health risks to individuals through unexpected exposure is greatly increased.
Habibeh Vosoughi, Hosein Azimian, Sara Khademi, Abdul-Rahim Rezaei, Maryam Najafi Amiri, Fereshteh vaziri-nezamdoost, Mohammad-taghi Bahreyni-Toossi   +6 more
doaj   +1 more source

Cellular sensitivity to low dose ionizing radiation

Journal of Radiation and Cancer Research, 2021
Cellular sensitivity to ionizing radiation is largely understood in terms of their DNA damage repair capacity. Efficient repair of DNA damage leaves irradiated cells unharmed. The observed differential responses of high doses (>500 mGy) and low doses (
Kaushala Prasad Mishra
doaj   +1 more source

Low-dose radiation pneumonitis [PDF]

Cancer, 1975
A case demonstrating fulminant radiation pneumonitis following a course of prophylactic whole lung irradiation at doses below 2000 rads, resulting in death, is presented. The importance of predisposing factors and the suspected "sensitizing" factor in this case are discussed.
S R, Braun, A, doPico, C E, Olson, W, Caldwell   +3 more
openaire   +2 more sources