Results 71 to 80 of about 655,412 (340)

Analysis of radiation-induced cell death in head and neck squamous cell carcinoma and rat liver maintained in microfluidic devices [PDF]

, 2013
Objective The aim of this study was to investigate how head and neck squamous cell carcinoma (HNSCC) tissue biopsies maintained in a pseudo in vivo environment within a bespoke microfluidic device respond to radiation treatment.
Burcombe R, Cai L, Eriksson D, Eriksson D, Fernberg JO, Hattersley SM, Hattersley SM, Ianzini F, Jemal A, Kamotani Y, Kroemer G, Lee P, Ma H, Mamouni J, Mansilla S, Mauk MG, Mirzaie-Joniani H, Mulhall HJ, Nevill JT, Parkin DM, Reddy AC, Remmerbach TW, Skoda C, Ts’ao C, Weigum SE, Withrow KP, Young EW, Ziober BL   +27 more
core   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Single institution implementation of permanent 131Cs interstitial brachytherapy for previously irradiated patients with resectable recurrent head and neck carcinoma [PDF]

, 2019
Purpose: Permanent interstitial brachytherapy is an appealing treatment modality for patients with locoregional recurrent, resectable head and neck carcinoma (HNC), having previously received radiation.
Bar-Ad, Voichita, Cognetti, David, Curry, Joseph, Doyle, Laura, Harrison, Amy, Hubley, Emily, Johnson, Jennifer, Keller, James, Luginbuhl, Adam, Peng, Cheng, To, David   +10 more
core   +1 more source

Patient-Specific Fetal Dose Determination for Multi-Target Gamma Knife Radiosurgery: Computational Model and Case Report. [PDF]

, 2017
A 42-year-old woman at 29 weeks gestation via in vitro fertilization who presented with eight metastatic brain lesions received Gamma Knife stereotactic radiosurgery (GKSRS) at our institution. In this study, we report our clinical experience and a ...
Braunstein, Steve, Ma, Lijun, McDermott, Michael, Paulsson, Anna K, Phillips, Justin, Sneed, Patricia K, Theodosopoulos, Philip V   +6 more
core   +1 more source

Low dose radiation, inflammation, cancer and chemoprevention [PDF]

International Journal of Radiation Biology, 2018
Recently, new studies have brought to light the potential risks of low dose radiation (LDR) in cancer. In this review, we discuss in detail the detrimental effects of LDR in some model organisms and animal models, as well as potential risks to human beings from some routine medical screening procedures.
Al Maqsudur Rashid, Latha Ramalingam, Arwa Al-Jawadi, Naima Moustaid-Moussa, Hanna Moussa   +4 more
openaire   +3 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Low Dose Radiation Adaptive Protection to Control Neurodegenerative Diseases

Dose-Response, 2014
Concerns have been expressed recently regarding the observed increased DNA damage from activities such as thinking and exercise. Such concerns have arisen from an incomplete accounting of the full effects of the increased oxidative damage.
Mohan Doss
doaj   +1 more source

Low-dose radiation cancer susceptibility models

Aging, 2015
While the biological effects of low-dose radiation exposure are increasingly better understood, continued research is needed to develop better individual risk-based models. Human population exposures to low doses of ionizing radiation (defined by the US Department of Energy as less than 10 rem or 0.1 Sv) are increasing due to occupational exposures of ...
Mao, Jian-Hua, Snijders, Antoine M
openaire   +4 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

In Vivo Mutagenic Effect of Very Low Dose Radiation

Dose-Response, 2006
Almost all of our knowledge about the mutational effect of radiation has come from high dose studies which are generally not relevant to public exposure.
Pamela J. Sykes, Tanya K. Day, Sarah J. Swinburne, Joanne M. Lane, Alexander A. Morley, Antony M. Hooker, Madhava Bhat   +6 more
doaj   +1 more source