Results 41 to 50 of about 184,530 (301)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Zero-field NMR J-Spectroscopy of Organophosphorus Compounds
, 2020 In this paper, we report the results of theoretical and experimental studies on basic organophosphorus compounds using zero-field NMR, where spin dynamics are investigated in the absence of a magnetic field with the dominant heteronuclear J-coupling. We
Piotr, Put +3 more
core +1 more source
Low-Field Benchtop NMR to Discover Early-Onset Sepsis: A Proof of Concept
Metabolites, 2023 Low-field (LF) benchtop NMR is a new family of instruments available on the market, promising for fast metabolic fingerprinting and targeted quantification of specific metabolites despite a lack of sensitivity and resolution with respect to high-field ...
Matteo Stocchero +5 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Analysis of Early Performance of Cement Paste by Low Field NMR
Applied Sciences, 2019 The change of the evaporable water content in the early hydration process of cement paste with different water-to-cement ratios was monitored by low field nuclear magnetic resonance (LF-NMR) relaxometry.
Dan Jin, Zejun Lang, Wu Yao
doaj +1 more source
Smooth deconvolution of low-field NMR signals
Analytica Chimica ActaLow resolution nuclear magnetic resonance (LR-NMR) is a common technique to identify the constituents of complex materials (such as food and biological samples). The output of LR-NMR experiments is a relaxation signal which can be modelled as a type of convolution of an unknown density of relaxation times with decaying exponential functions, plus ...
Gianluca Frasso, Paul H.C. Eilers
openaire +2 more sources
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
MoleculesRecently, benchtop nuclear magnetic resonance (NMR) spectrometers utilizing permanent magnets have emerged as versatile tools with applications across various fields, including food and pharmaceuticals.
Camille Pujol +6 more
doaj +1 more source
Monitoring Electrochemical Reactions in Situ with Low Field NMR: A Mini-Review
Applied Sciences, 2019 The number of applications of time domain NMR using low-field spectrometers in research and development has been steadily increasing in recent years with applications ranging from quality control of industrial products to the study of physical and ...
Bruna Ferreira Gomes +2 more
doaj +1 more source
Water partitioning and migration in unsaturated bentonites by low‐field NMR characterization
Vadose Zone Journal, 2023 Water behavior in bentonite clay pores is influenced by soil–water interaction mechanisms such as capillary and adsorptive forces. Quantitative measurement of these water statuses remains challenging, leading to the adoption of advanced techniques.
Ling Peng, Fan Zhang, Yi Dong, Chi Zhang
doaj +1 more source