Results 91 to 100 of about 33,320 (244)

A Review of “Access to Care” Issues in Aortic Stenosis Patients: A Negative Report Card

Structural Heart
The identification and management of patients with aortic stenosis exist along a continuum that includes healthy living, latent progression, diagnosis, treatment, and posttreatment recovery.
Adam M. Reisman, MD, Sammy Elmariah, MD, MPH   +1 more
doaj   +1 more source

Prediction of symptom development and aortic valve replacement in patients with low-gradient severe aortic stenosis

European Heart Journal Open
Aims Current evidence on the prognostic value of exercise stress echocardiography (ESE) in asymptomatic patients with low-gradient severe aortic stenosis (AS) is limited.
D. Miyahara, M. Izumo, Yukio Sato, Tatsuro Shoji, Risako Murata, Ryutaro Oda, T. Okuno, S. Kuwata, Y. Akashi   +8 more
semanticscholar   +1 more source

Multi‐Functional S‐HA/ASTA NPs Coating on Biodegradable ZE21B Alloy for Cerebrovascular Applications

Rare Metals, EarlyView.
ABSTRACT Magnesium (Mg) and its alloys have attracted extensive attention of researchers in the field of cerebrovascular implants due to their good mechanical properties and biosafety. However, rapid degradation and delayed endothelialization pose challenges. To address these issues, this study introduces a multifunctional composite coating.
Aqeela Yasin, Mujahid Iqbal, Yachen Hou, Jingan Li, Shaokang Guan   +4 more
wiley   +1 more source

Comparison of Early Surgical or Transcatheter Aortic Valve Replacement Versus Conservative Management in Low‐Flow, Low‐Gradient Aortic Stenosis Using Inverse Probability of Treatment Weighting: Results From the TOPAS Prospective Observational Cohort Study

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2020
Background No randomized comparison of early (ie, ≤3 months) aortic valve replacement (AVR) versus conservative management or of transcatheter AVR (TAVR) versus surgical AVR has been conducted in patients with low‐flow, low‐gradient (LFLG) aortic ...
M. Annabi, N. Côté, A. Dahou, P. Bartko, J. Bergler-Klein, I. Burwash, S. Orwat, H. Baumgartner, J. Mascherbauer, G. Mundigler, M. Fukui, J. Cavalcante, H. Ribeiro, J. Rodés‐Cabau, M. Clavel, P. Pibarot   +15 more
semanticscholar   +1 more source

Cardiovascular Health in Women—Across the Lifespan

Clinical Endocrinology, EarlyView.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar, Jessica Yao, Simone Gong, Madhuka Wijayarathne, Monique Watts, Swati Mukherjee   +5 more
wiley   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

Outcome of Normal‐Flow Low‐Gradient Severe Aortic Stenosis With Preserved Left Ventricular Ejection Fraction: A Propensity‐Matched Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Normal‐flow, low‐gradient severe aortic stenosis (NF‐LG‐SAS), defined by aortic valve area
Gagandeep Chadha, Yohann Bohbot, Dan Rusinaru, Sylvestre Maréchaux, Christophe Tribouilloy   +4 more
doaj   +1 more source

Comparative analysis of metabolic and functional cardiac alterations in diet‐ and genetically induced mouse models of cardiac dysfunction

The FEBS Journal, EarlyView.
Dietary and genetic stress trigger different routes to heart failure. In mice, a carbohydrate‐free high‐fat diet caused mitochondrial dysfunction and impaired energy production with preserved pumping function, while genetic obesity led to heart enlargement, fibrosis, and reduced function.
Christiane Ott, Patricia Baumgarten, Thorsten Henning, Daniela Weber, Iwona Wallach, Jana Grune, Ulrich Kintscher, Hermann‐Georg Holzhütter, Tilman Grune, Nikolaus Berndt   +9 more
wiley   +1 more source

Bilateral dynamic cerebral autoregulation assessment during endovascular treatment in large‐vessel occlusion stroke

Experimental Physiology, EarlyView.
Abstract Recanalization by endovascular treatment (EVT) is effective in acute ischaemic stroke caused by large‐vessel occlusion. Better understanding of the pathophysiology could possibly identify targets for improving peri‐procedural management and thereby patient outcome.
Adam Vittrup Heiberg, Troels Gil Lukassen, Thomas Clement Truelsen, Henrik Gutte Borgwardt, Goetz Benndorf, Christine Sølling, Henrik Winther Schytz, Klaus Hansen, Kirsten Møller, Helle Klingenberg Iversen   +9 more
wiley   +1 more source

Aortic Stenosis: The Old Disease With New (and Evolving) Faces

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Calvin Woon‐Loong Chin
doaj   +1 more source