Results 71 to 80 of about 36,005 (238)

Optimizing Diagnostic Accuracy of Clinical Red Flags in RASopathies

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT RASopathies are a group of genetic disorders caused by pathogenic variants in the RAS‐mitogen‐activated protein kinase (RAS–MAPK) signaling pathway, often presenting with congenital heart defects, craniofacial dysmorphisms, and developmental delays. To assess the diagnostic yield of genetic testing in patients with suspected RASopathies and to
Emanuele Bobbio, Martina Caiazza, Emanuele Monda, Giustina Aruta, Alberto Budillon, Augusto Esposito, Adelaide Fusco, Annapaola Cirillo, Marta Rubino, Immacolata Viscovo, Gioacchino Scarano, Matteo Della Monica, Vincenzo Nigro, Giulio Piluso, Leandro Pecchia, Maria Giovanna Russo, Giuseppe Limongelli   +16 more
wiley   +1 more source

Transfemoral aortic valve replacement in a nonagenarian with aortic stenosis and cardiac amyloidosis: case report

Journal of Cardiothoracic Surgery, 2022
Background Cardiac amyloidosis (CA) is diagnosed with increasing frequency in the elderly population with severe aortic stenosis (AS), especially with the low-flow, low- gradient phenotype. Prognosis is poor with no treatment.
Deena Akras, Keith Bullinger, Meera Kondapaneni, Aisha Siraj, Rami Akhrass, Ashish Aneja   +5 more
doaj   +1 more source

Balloon Aortic Valvuloplasty as Bridge-to-Decision in High Risk Patients with Severe Aortic Valve Stenosis [PDF]

, 2015
Background. A sizable group of patients with symptomatic aortic stenosis (AS) can undergo neither surgical aortic valve replacement (AVR) nor transcatheter aortic valve implantation (TAVI) because of clinical contraindications.
Bordoni, Barbara <1980>
core   +1 more source

Porcine kidney xenotransplantation: From primate models to clinical reality

Animal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo, Ling Zhang, Shoulong Deng, Chuan Qin   +3 more
wiley   +1 more source

Contemporary Outcomes in Low‐Gradient Aortic Stenosis Patients Who Underwent Dobutamine Stress Echocardiography

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Detection of flow reserve (FR) by dobutamine stress echocardiography is used for risk stratification in low‐gradient aortic stenosis (AS).
Kimi Sato, Kesavan Sankaramangalam, Krishna Kandregula, Jennifer A. Bullen, Samir R. Kapadia, Amar Krishnaswamy, Stephanie Mick, L. Leonardo Rodriguez, Richard A. Grimm, Venu Menon, Milind Y. Desai, Lars G. Svensson, Brian P. Griffin, Zoran B. Popović   +13 more
doaj   +1 more source

Final 5-year clinical and echocardiographic results for treatment of severe aortic stenosis with a self-expanding bioprosthesis from the ADVANCE Study. [PDF]

, 2017
Aims: The ADVANCE study was designed to evaluate the safety and effectiveness of transcatheter aortic valve implantation (TAVI) with a self-expanding bioprosthesis in real-world patients with symptomatic, severe aortic stenosis at high surgical risk for ...
Adams, Axel Linke, Barbanti, Bosmans, Brecker, Corrado Tamburino, Deeb, Duncan, Egbe, Grube, Jia Guo, Johan Bosmans, Joint Task Force on the Management of Valvular Heart Disease of the European Society of (ESC), European Association for Cardio-Thoracic Surgery (EACTS), Kapadia, Kappetein, Kleiman, Leon, Leon, Leon, Linke, Mack, Makkar, Makkar, Peter Wenaweser, Piazza, Popma, Reardon, Sabine Bleiziffer, Sondergaard, Sondergaard, Stephen Brecker, Ulrich Gerckens, Van Belle, Yakubov   +33 more
core   +1 more source

Radial capacity and hemodynamics evaluation in vitro and implantable feasibility validation in vivo of thinner bioresorbable polymer vascular stents

BMEMat, EarlyView.
A series of in vitro experiments, numerical simulations and in vivo experiments were conducted to jointly evaluate the effects of different thicknesses of bioabsorbable polymer vascular stents on their radial capacity, hemodynamics and in vivo outcomes.
Chong Chen, Tao Li, Zhongyou Li, Jingyuan Zhou, Zhuo Zhang, Yan Xiong, Rifang Luo, Yu Chen, Yunbing Wang, Ping Fu   +9 more
wiley   +1 more source

Case report: Stenosis turned leak … and turned stenosis—complications of paravalvular prosthetic leak closure with a plug device

Frontiers in Cardiovascular Medicine, 2023
BackgroundParavalvular leak is one of the most common complications and is among the most important prognostic factors of short- and long-term mortality after transcatheter aortic valve implantation (TAVI). Percutaneous valvular leak repair constitutes a
Barbara Pitta Gros, Barbara Pitta Gros, Olivier Roux, Eric Eeckhout, Eric Eeckhout, Matthias Kirsch, Matthias Kirsch   +6 more
doaj   +1 more source

Renal artery stenosis-when to screen, what to stent? [PDF]

, 2014
Renal artery stensosis (RAS) continues to be a problem for clinicians, with no clear consensus on how to investigate and assess the clinical significance of stenotic lesions and manage the findings.
A Losito, A Persu, AH Cragg, Alison Severn, Antiplatelet Trialists’ Collaboration, AR Chade, AT Hirsch, B Bruyne De, B Drieghe, B Girolami, BC Jaarsveld van, BH Gray, C Chrysochou, C Chrysochou, C Rountas, CG Missouris, CJ Cooper, CJ Cooper, Claudine G. Jennings, CM Cheung, D Blondin, D Lao, D Mukherjee, DFJ Tollefson, DG Hackam, DP Slovut, DTNA Berg van den, E Balk, FH Messerli, GA McKenzie, GBC Vasbinder, GBC Vasbinder, GJ Williams, H Tan, H Weibull, Isla S. Mackenzie, J Ritchie, J Webster, JL Zhang, John G. Houston, JP Beregi, JV Smit, JW Olin, JW Olin, K Rocha-Singh, K Wheatley, KA Gillis, KJ Hansen, L Bax, L Trinquart, LD Dworkin, LE Ramsay, LM Messina, LU Mailloux, M Seddon, MC Bates, MJ Bloch, MT Caps, MW Burket, OW Kincaid, P Liang, PJ Conlon, PJG Ven van de, PJG Ven van de, Renal Association, S Anand, S Savard, S Willoteaux, Samira Bell, SC Textor, SC Textor, SC Textor, SJ Gandy, SJ Gandy, SM Begelman, SW Lim, T Jonason, Thomas M. MacDonald, TP Murphy, VS Silva, WJ Jean   +80 more
core   +4 more sources

Drug‐coated balloons: From conventional designs to next‐generation innovations in vascular therapy

BMEMat, EarlyView.
This review traces the evolution of drug‐coated balloons (DCBs) from conventional designs to next‐generation platforms. We highlight innovations in balloon engineering, coating technologies, and therapeutic agents that enhance localized drug delivery while addressing challenges in efficiency, safety, and biocompatibility for vascular and emerging non ...
Lu Zhang, Jiawei Cui, Jin Wang, Manfred F. Maitz, Rifang Luo, Yunbing Wang   +5 more
wiley   +1 more source