Results 61 to 70 of about 9,037,523 (220)

Sigmoid isostiffness-lines: An in-vitro model for the assessment of aortic stenosis severity

Frontiers in Cardiovascular Medicine, 2022
IntroductionThe aortic valve opening area (AVA), used to quantify aortic stenosis severity, depends on the transvalvular flow rate (Q). The currently accepted clinical echocardiographic method assumes a linear relation between AVA and Q.
Eric Buffle, Eric Buffle, Michael Stucki, Michael Stucki, Shaokai Zheng, Maxime Chiarelli, Christian Seiler, Dominik Obrist, Stefano F. de Marchi   +8 more
doaj   +1 more source

Diagnosis of “Paradoxical” Low-Gradient Aortic Stenosis Patients

Journal of the American College of Cardiology, 2013
The report by Lauten et al. [(1)][1] investigates a very important clinical presentation—“paradoxical” low-gradient aortic stenosis (PLG AS). This is a diagnostic challenge, and their work definitely improves our understanding of this problem.
Saikrishnan, Neelakantan, Yoganathan, Ajit P., Kumar, Gautam   +2 more
openaire   +2 more sources

Aortic valve disease: Novel animal models for advancing our understanding of the underlying mechanisms

Animal Models and Experimental Medicine, EarlyView.
Due to the complex pathophysiology of aortic valve disease (AVD) and the resulting lack of effective pharmacotherapy, existing animal models are valuable research tools, but each has its own strengths and limitations. This review systematically surveys the major AVD models, compares their induction methods, pathological features, advantages and ...
Liya Hou, Xue Liu, Wangxing Hu, Xianbao Liu, Wei Zhu   +4 more
wiley   +1 more source

Silk Fibroin for Cardiovascular Medical Devices: Review of Material Properties, Applications, and Clinical Potential

Advanced NanoBiomed Research, EarlyView.
Silk fibroin is an attractive natural biomaterial that can be engineered into diverse cardiovascular constructs, including vascular grafts, cardiac patches, heart valves, and stent coatings. Its tunable biological and mechanical properties have driven substantial preclinical progress; however, widespread clinical translation in cardiovascular ...
Mahsa Haghighattalab, Matt Govendir, Kristina Andelovic, Zachary Och, Fatemeh Karimi, Munira Xaymardan, Tomasz Jungst, Jelena Rnjak‐Kovacina, Nona Farbehi   +8 more
wiley   +1 more source

Estenosis aórtica de bajo flujo y bajo gradiente

Revista Colombiana de Cardiología, 2019
Resumen: La estenosis valvular aórtica es la valvulopatía más frecuente y en los últimos años ha sido admirable el avance tanto en su aproximación diagnóstica como terapéutica, dado el advenimiento del reemplazo de válvula aórtica transcatéter y ...
José Luis Zamorano, Jaime Alberto Rodríguez P., Miguel Venegas M.   +2 more
doaj   +1 more source

Subthreshold Aortic Valve Calcium Scores in Severe Aortic Stenosis and Transthyretin Cardiac Amyloidosis

JACC: Case Reports, 2020
We have clinically observed that some patients with transthyretin cardiac amyloidosis and severe aortic stenosis may have lesser degrees of calcification than one might expect.
Muzna Hussain, MD, Mazen Hanna, MD, Leonardo Rodriguez, MD, Brian Griffin, MD, Chris Watson, MD PhD, Dermot Phelan, MD, Paul Schoenhagen, MD, Wael Jaber, MD, Paul Cremer, MD, Patrick Collier, MD, PhD   +9 more
doaj   +1 more source

Assessment of low-flow, low-gradient, severe aortic stenosis: an invasive evaluation is required for decision making.

, 2014
Low-flow, low-gradient severe aortic stenosis (AS) is characterised by a small aortic valve area (AVA) and low mean gradient (MG) secondary to a low cardiac output and may occur in patients with either a preserved or reduced left ventricular ejection ...
Windecker, Stephan, Praz, Fabien, O'Sullivan, Crochan John, Wenaweser, Peter Martin, Stortecky, Stefan   +4 more
core   +1 more source

Non-compaction cardiomyopathy with low-gradient aortic valve stenosis [PDF]

European Heart Journal, 2008
A 73-year-old man presented to the emergency department with dyspnea of 2 days duration. Auscultation of the precordium was notable for a grade 2/6 systolic murmur. Echocardiography revealed a highly impaired left ventricular function and a calcified aortic valve stenosis with a …
Steffen P, Schoen, Ruth H, Strasser, Utz, Kappert   +2 more
openaire   +2 more sources

Validation of an Automated Artificial Intelligence‐Driven Planner for Transcatheter Aortic Valve Replacement

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Preprocedural planning with multislice computed tomography (MSCT) is an essential prerequisite for successful transcatheter aortic valve replacement (TAVR). However, preprocedural planning is time‐consuming and may contain clinically meaningful interobserver variability.
Mark M. P. van den Dorpel, Lucas Uchoa de Assis, Jenna van Niekerk, Sophie Deckx, Matthew Sherman, Janelle Schrot, Anna Kozak, Isabella Kardys, Alexander Hirsch, Joost Daemen, Rutger Jan Nuis, Nicolas M. Van Mieghem   +11 more
wiley   +1 more source

LES of non-Newtonian physiological blood flow in a model of arterial stenosis [PDF]

, 2012
Large Eddy Simulation (LES) is performed to study the physiological pulsatile transition-to-turbulent non-Newtonian blood flow through a 3D model of arterial stenosis by using five different blood viscosity models: (i) Power-law, (ii) Carreau, (iii ...
Molla, M.M., M.C. Paul, M.M. Molla, Paul, M.C.   +3 more
core   +1 more source