High-sensitivity troponin I concentrations are a marker of an advanced hypertrophic response and adverse outcomes in patients with aortic stenosis [PDF]
Aims: High-sensitivity cardiac troponin I (cTnI) assays hold promise in detecting the transition from hypertrophy to heart failure in aortic stenosis.
A. L. Hunter +23 more
core +5 more sources
Biological niches within human calcified aortic valves. Towards understanding of the pathological biomineralization process [PDF]
Despite recent advances, mineralization site, its microarchitecture, and composition in calcific heart valve remain poorly understood. A multiscale investigation, using scanning electron microscopy (SEM), transmission electron microscopy (TEM), and ...
Cavarretta, Elena +6 more
core +7 more sources
Imaging of Low-Gradient Severe Aortic Stenosis
Although most patients with severe aortic stenosis (AS) have high peak velocity and mean transvalvular gradient, there is a subset of patients with low-flow, low-gradient severe AS (LGSAS). Assessment and management of such patients can be difficult and dobutamine echocardiography has been recommended to distinguish those with pseudo-AS (low calculated
Tandon, Anumeha, Grayburn, Paul A.
openaire +2 more sources
Aortic Stenosis Suspected to Be Severe Despite Low Gradients [PDF]
The American College of Cardiology/American Heart Association and European Society of Cardiology/European Association for Cardio-Thoracic Surgery guidelines generally recommend aortic valve replacement (AVR) in patients with severe aortic stenosis (AS) who have symptoms, have left ventricular (LV) systolic dysfunction, or undergo coronary artery bypass
Philippe, Pibarot, Jean G, Dumesnil
openaire +2 more sources
Bridging aortic valve surgery to 21st century. what can a surgeon do [PDF]
Aortic valve stenosis is the most clinically relevant valvular heart disease in the elderlies. Surgical aortic valve replacement (SAVR) represented, for decades, the standard of care for the treatment of severe aortic stenosis.
Barretta, Antonio +13 more
core +1 more source
Arrhythmic risk in elderly patients candidates to transcatheter aortic valve replacement. predicative role of repolarization temporal dispersion [PDF]
Degenerative aortic valve stenosis (AS) is associated to ventricular arrhythmias and sudden cardiac death, as well as mental stress in specific patients. In such a context, substrate, autonomic imbalance as well as repolarization dispersion abnormalities ...
Crapanzano, Davide +11 more
core +1 more source
Low “gradient”, low flow aortic stenosis [PDF]
Aortic stenosis is thought to have a long, asymptomatic latent phase during which the risk of sudden death is low. In fact symptoms can be revealed by treadmill exercise in a large proportion of apparently asymptomatic patients.1 Patients may limit exercise to avoid symptoms or may fail to recognise the presence of exertional breathlessness or ascribe ...
openaire +2 more sources
Percutaneous pulmonary valve implantation in humans - Results in 59 consecutive patients [PDF]
Background - Right ventricular outflow tract (RVOT) reconstruction with valved conduits in infancy and childhood leads to reintervention for pulmonary regurgitation and stenosis in later life.Methods and Results - Patients with pulmonary regurgitation ...
Bonhoeffer, P +12 more
core +1 more source
Aortic stenosis (AS) causes left ventricular outflow obstruction. Severe AS has major haemodynamic implications in critically ill patients, in whom increased cardiac output and oxygen delivery are often required.
Jeroen Walpot +3 more
doaj +1 more source
Background A retrospective comparative study was designed to determine whether the transvalvular gradient has a predictive value in the assessment of operative outcome in patients with severe aortic stenosis and poor left ventricular function.
Vchivkov Ilja +3 more
doaj +1 more source

