Results 131 to 140 of about 51,426 (322)

Phenotype characterization of heart failure with preserved ejection fraction in medical device and surgical trials

open access: yesESC Heart Failure, EarlyView.
This systematic review identified 24 clinical trials of medical device and surgical interventions for HFpEF, with 16 demonstrating at least safety and feasibility, but little evidence of long‐term benefit. Phenotype‐based responses suggest that certain interventions may benefit specific HFpEF subgroups, yet most trials suffered from heterogeneous ...
Kurdo Araz   +5 more
wiley   +1 more source

Surrogates for myocardial power and power efficiency in patients with aortic valve disease [PDF]

open access: yes, 2019
We aimed to assess surrogate markers for left ventricular (LV) myocardial power and efficiency in patients with isolated aortic stenosis (AS) and combined stenosis/regurgitation (AS/AR).
Berger, Felix   +8 more
core   +1 more source

SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI

open access: yesESC Heart Failure, EarlyView.
Abstract In the 2021 European Society of Cardiology (ESC) heart failure (HF) guidelines, sodium–glucose cotransporter 2 (SGLT2) inhibitors were recommended for the prevention of HF in patients with type 2 diabetes mellitus (T2DM) and for the treatment of HF with reduced ejection fraction (HFrEF).
Marco Metra   +25 more
wiley   +1 more source

Haemodynamic Patterns of Severe Aortic Stenosis

open access: yesРациональная фармакотерапия в кардиологии, 2020
The authors present up-to-date review of clinical pathophysiology of aortic stenosis (AS) based on differentiation of its haemodynamic patterns, and some actual issues of instrumental diagnostics and classification of AS.
A. E. Komlev   +4 more
doaj   +1 more source

First evaluation of a novel pulsatile LVAD: Feasibility and haemodynamic impact in acute heart failure

open access: yesESC Heart Failure, EarlyView.
The pulsatile ventricular assist platform (pVAP) was connected to a membrane pump in six large swine models. The system, driven by a conventional intra‐aortic balloon pump console (IABP), was utilized to drain left atrial blood during systole and to eject the collected blood back into the ascending aorta during diastole.
Sara Knigge   +11 more
wiley   +1 more source

Aortic Stenosis: The Old Disease With New (and Evolving) Faces

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Calvin Woon‐Loong Chin
doaj   +1 more source

Impact of epicardial adipose tissue on myocardial function and structure in patients with severe aortic valve stenosis

open access: yesESC Heart Failure, EarlyView.
Epicardial adipose tissue (EAT) has been linked to adverse remodelling and outcomes in aortic valve stenosis (AS), yet mechanisms remain unclear. In 137 patients with severe AS undergoing CMR before TAVR, higher EAT (≥46.5 ml/m2) was associated with impaired left atrial (LA) reservoir strain, while ventricular morphology, function and tissue ...
Judith Gronwald   +10 more
wiley   +1 more source

Low-gradient aortic stenosis in patients with concomitant mitral regurgitation - a subgroup analysis from the German aortic valve registry (GARY) [PDF]

open access: bronze, 2021
Brunilda Alushi   +5 more
openalex   +1 more source

Numerical Modeling of Pulse Wave Propagation in a Stenosed Artery using Two-Way Coupled Fluid Structure Interaction (FSI)

open access: yes, 2018
As the heart beats, it creates fluctuation in blood pressure leading to a pulse wave that propagates by displacing the arterial wall. These waves travel through the arterial tree and carry information about the medium that they propagate through as well ...
Gamage, Peshala P. T   +2 more
core   +1 more source

Adaptation of right ventricular function following tricuspid transcatheter edge‐to‐edge repair

open access: yesESC Heart Failure, EarlyView.
Right ventricular remodelling following tricuspid transcatheter edge‐to‐edge repair. After T‐TEER, most patients either maintain or decrease their RVEF, while only a minority experience an increase. Patients with increased RVEF were associated with TR worsening and worse prognosis.
Sara Bombace   +12 more
wiley   +1 more source

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