Cellular and extracellular proteomic profiling of paradoxical low-flow low-gradient aortic stenosis myocardium [PDF]
AimsPatients with severe aortic stenosis (AS), low transvalvular flow (LF) and low gradient (LG) with normal ejection fraction (EF)—are referred to as paradoxical LF-LG AS (PLF-LG).
Manar Elkenani +27 more
doaj +3 more sources
Contemporary Outcomes in Low‐Gradient Aortic Stenosis Patients Who Underwent Dobutamine Stress Echocardiography [PDF]
Background Detection of flow reserve (FR) by dobutamine stress echocardiography is used for risk stratification in low‐gradient aortic stenosis (AS).
Kimi Sato +13 more
doaj +3 more sources
Cardiac Reversibility and Survival After Transcatheter Aortic Valve Implantation in Patients With Low-Gradient Aortic Stenosis. [PDF]
Background Prognostic implications of transcatheter aortic valve implantation (TAVI) in low‐gradient (LG) aortic stenosis (AS) remain controversial.
Sato K +24 more
europepmc +2 more sources
Dobutamine stress echocardiography in paradoxical low-flow, low-gradient aortic stenosis with mitral regurgitation. [PDF]
An 86-year-old man was referred to our hospital with heart failure. Transthoracic echocardiography (TTE) demonstrated paradoxical low-flow, low-gradient aortic stenosis (AS) (stroke volume index, 26.2 mL/m 2 ; aortic valve area calculated with the ...
Taniguchi T +4 more
europepmc +2 more sources
Outcomes From Transcatheter Aortic Valve Replacement in Patients With Low-Flow, Low-Gradient Aortic Stenosis and Left Ventricular Ejection Fraction Less Than 30% [PDF]
Importance In low-flow, low-gradient aortic stenosis (LFLG AS), the severity of left ventricular dysfunction remains a key factor in the evaluation of aortic valve replacement.
Frédéric Maes +32 more
openalex +2 more sources
Multimodality imaging methods and systemic biomarkers in classical low-flow low-gradient aortic stenosis: Key findings for risk stratification. [PDF]
Objectives The aim of the present study is to assess multimodality imaging findings according to systemic biomarkers, high-sensitivity troponin I (hsTnI) and B-type natriuretic peptide (BNP) levels, in low-flow, low-gradient aortic stenosis (LFLG-AS ...
Lopes MAAAM +15 more
europepmc +2 more sources
TAVI in patients with low-flow low-gradient aortic stenosis-short-term and long-term outcomes. [PDF]
The study objective was to characterize different groups of low-flow low-gradient (LFLG) aortic stenosis (AS) and determine short-term outcomes and long-term mortality according to Valve Academic Research Consortium-3 (VARC-3) endpoint definitions ...
Steffen J +15 more
europepmc +2 more sources
Low-flow, Low-gradient Severe Aortic Stenosis: A Review [PDF]
Aortic stenosis (AS) is a common valve pathology experienced by patients worldwide. There are limited population-based studies assessing its prevalence; however, epidemiological studies emphasize that the burden of disease is growing.
Nishant Sharma +2 more
openalex +2 more sources
Right ventricular dysfunction and impaired right ventricular-pulmonary arterial coupling in paradoxical low-flow, low-gradient aortic stenosis. [PDF]
Paradoxical low‐flow, low‐gradient aortic stenosis (pLFLG AS) may represent a diagnostic challenge, and its pathophysiology is complex. While left ventricular (LV) systolic function is preserved, right ventricular dysfunction (RVD) and consecutive LV ...
Nies RJ +11 more
europepmc +2 more sources
Left Ventricle Biomechanics of Low-Flow, Low-Gradient Aortic Stenosis: A Patient-Specific Computational Model. [PDF]
This study aimed to create an imaging-derived patient-specific computational model of low-flow, low-gradient (LFLG) aortic stenosis (AS) to obtain biomechanics data about the left ventricle.
Wisneski AD +8 more
europepmc +2 more sources

