Results 201 to 210 of about 54,299 (247)

The AUTACE That Degrades KRAS and Engages CD8+ T Cells for the Treatment of KRAS/TP53 Co‐Mutant Tumors

Advanced Science, EarlyView.
AUTACE is a bifunctional nanoplatform that integrates tumor targeting, immune engagement, and on‐demand KRAS degradation. It targets KRAS/TP53 co‐mutant tumors via TP53‐specific TCRs, elicits antitumor CD8+ T‐cell responses through surface anti‐CD3 antibodies, and uses low‐intensity focused ultrasound (LIFU) to trigger controlled release of the KRAS ...
Luo Li, Bolin Li, Yanan Hao, Bo Pang, Pan Li, Chunli Li, Yu Tang   +6 more
wiley   +1 more source

Low-Intensity Focused Ultrasound to the Human Dorsal Anterior Cingulate Attenuates Acute Pain Perception and Autonomic Responses. [PDF]

J Neurosci
Strohman A, Payne B, In A, Stebbins K, Legon W.   +4 more
europepmc   +1 more source

Effect of Alkyl Chain Length on the Bandgap, Ferroelectric, and Photoelectric Properties of Lead‐Based Molecular Ferroelectrics

Advanced Science, EarlyView.
This study develops a novel 2D molecular ferroelectric [C6N2H18]PbI4 with polarization enhanced photovoltaics. It systematically investigates the effect of alkylamine spacer cation chain lengths on the band gap, ferroelectric, and photoelectric properties, offering new design strategies.
Ganghua Zhang, Jinrong Wen, Ping Chen, Zhibo Chen, Pingying Tang, Dezeng Li, Jingshan Hou, Yongzheng Fang   +7 more
wiley   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Janus microparticles-based targeted and spatially-controlled piezoelectric neural stimulation via low-intensity focused ultrasound. [PDF]

Nat Commun
Han M, Yildiz E, Bozuyuk U, Aydin A, Yu Y, Bhargava A, Karaz S, Sitti M.   +7 more
europepmc   +1 more source

Transcranial Low-Intensity Focused Ultrasound Stimulation of the Visual Thalamus Produces Long-Term Depression of Thalamocortical Synapses in the Adult Visual Cortex. [PDF]

J Neurosci
Mesik L, Parkins S, Severin D, Grier BD, Ewall G, Kotha S, Wesselborg C, Moreno C, Jaoui Y, Felder A, Huang B, Johnson MB, Harrigan TP, Knight AE, Lani SW, Lemaire T, Kirkwood A, Hwang GM, Lee HK.   +18 more
europepmc   +1 more source

Low-intensity focused ultrasound to human amygdala reveals a causal role in ambiguous emotion processing and alters local and network-level activity

Algermissen J, Rascu M, Weber LA, Boer Td, Martin E, Treeby B, Gray M, Cleveland RO, Wittmann MK, Clarke WT, Fouragnan E, Rushworth MF, Klein-Flügge MC.   +12 more
europepmc   +1 more source

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Low-Intensity Focused Ultrasound Produces Immune Response in Pancreatic Cancer

Ultrasound in Medicine & Biology, 2022
Pancreatic adenocarcinoma is an aggressive malignancy with limited therapeutic treatments available and a 5-y survival less than 10%. Pancreatic cancers have been found to be immunogenically "cold" with a largely immunosuppressive tumor microenvironment. There is emerging evidence that focused ultrasound can induce changes in the tumor microenvironment
Jordan B, Joiner, Nancy P, Kren, Phillip G, Durham, Autumn J, McRee, Paul A, Dayton, Yuliya, Pylayeva-Gupta   +5 more
openaire   +2 more sources

Low Intensity Focused Ultrasound Modulation of Vincristine Induced Neuropathy

Neuroscience, 2020
Previously, we showed internal low intensity focused ultrasound (liFUS) improves nociceptive thresholds in rats with vincristine-induced neuropathy (VIN) for 48-h post-treatment. Here, we perform more rigorous behavioral testing with the internal device and introduce external liFUS treatment.
Abigail, Hellman, Teresa, Maietta, Kanakaharini, Byraju, Yunseo, Linda Park, Miriam, Shao, Andrea, Liss, Paul, Neubauer, Clif, Burdette, Goutam, Ghoshal, Jiang, Qian, Julia, Nalwalk, Julie G, Pilitsis   +11 more
openaire   +2 more sources