Results 131 to 140 of about 474,549 (168)

Low-Level Primary Blast Causes Acute Ocular Trauma in Rabbits

Journal of Neurotrauma, 2016
The objective of this study was to determine whether clinically significant ocular trauma can be induced by a survivable isolated primary blast using a live animal model. Both eyes of 18 Dutch Belted rabbits were exposed to various survivable low-level blast overpressures in a large-scale shock tube simulating a primary blast similar to an improvised ...
Kirstin, Jones, Jae-Hyek, Choi, William E, Sponsel, Walt, Gray, Sylvia L, Groth, Randolph D, Glickman, Brian J, Lund, Matthew A, Reilly   +7 more
openaire   +2 more sources

Low levels of ABCG2 expression in adult AML blast samples

Blood, 2002
Previous reports have suggested that the adenosine triphosphate–binding cassette protein ABCG2 (breast cancer resistance protein [BCRP], mitoxantrone resistance [MXR]) is associated with drug resistance in acute myeloid leukemia (AML). The aims of this study were to determine the level of ABCG2 mRNA expression necessary to produce drug resistance and ...
Brian L, Abbott, Anne-Marie, Colapietro, Yuxiao, Barnes, Frank, Marini, Michael, Andreeff, Brian P, Sorrentino   +5 more
openaire   +2 more sources

Pathophysiology of blast‐induced ocular trauma in rats after repeated exposure to low‐level blast overpressure

Clinical & Experimental Ophthalmology, 2014
AbstractBackgroundThe incidence of blast‐induced ocular injury has dramatically increased due to advances in weaponry and military tactics. A single exposure to blast overpressure (BOP) has been shown to cause damage to the eye in animal models; however, on the battlefield, military personnel are exposed to BOP multiple times.
Jae Hyek, Choi, Whitney A, Greene, Anthony J, Johnson, Mikulas, Chavko, Jeffery M, Cleland, Richard M, McCarron, Heuy-Ching, Wang   +6 more
openaire   +2 more sources

Low levels of blast raises intracranial pressure and impairs cognitive function in rats

Journal of Neurotrauma, 2009
Brain injury after high-level blast has been established both clinically and experimentally. Less is known about the effects on the brain of exposure to low to moderate blast levels, such as those encountered by military personnel during the firing of weapons.
Annette, Säljö, Berndt, Svensson, Maria, Mayorga, Anders, Hamberger, Hayde, Bolouri   +4 more
openaire   +2 more sources

Relation of Repeated Low-Level Blast Exposure With Symptomology Similar to Concussion

Journal of Head Trauma Rehabilitation, 2015
To investigate anecdotal reports suggesting that repeated exposure to low-level explosive blast has myriad health impacts, including an array of neurological effects.A total of 184 anonymous survey respondents from military and nonmilitary law enforcement populations (135 exposed to occupational blast and 49 controls).Survey of self-reported history of
Walter, Carr, Elena, Polejaeva, Anna, Grome, Beth, Crandall, Christina, LaValle, Stephanie E, Eonta, Lee Ann, Young   +6 more
openaire   +2 more sources

Low-Level Blast Exposure in Humans A Systematic Review of Acute and Chronic Effects

Journal of Special Operations Medicine, 2020
There is growing concern that military breaching and training and firing artillery and mortars, grenades, and shoulder-fired weapons may have some type of cumulative deleterious effects. There are anecdotal reports of those with repetitive exposure to low-level blast complaining of various symptoms, as well as increasing empirical evidence. The purpose
Heather G, Belanger, F, Bowling, Eveline F, Yao   +2 more
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Mild Traumatic Brain Injury From Repeated Low-Level Blast Exposures

Volume 3: Biomedical and Biotechnology Engineering, 2015
Recent studies on military breachers in training environments suggest that there are neurocognitive risks from exposure to repeated low-level blasts. However, the dose accumulation effects from multiple low-level blast exposures and their relation to mild traumatic brain injury (mTBI) are not well understood.
Jessica M. Wong, Adam L. Halberstadt, Humberto A. Sainz, Kiran S. Mathews, Brian W. Chu, Laurel J. Ng, Philemon C. Chan   +6 more
openaire   +1 more source

The Effects of Low-level Repetitive Blasts on Neuropsychological Functioning

2015
Abstract : Despite increased research on blast-related mild traumatic brain injury (mTBI), relatively little is understood about long-term symptomatology. The primary objective of this study was to determine whether repeated exposure to low-level controlled blasts produces observable changes in cognitive functioning and psychological health. The target
William A Ahroon, Michael N Dretsch, Kenneth J Thiel   +2 more
openaire   +1 more source

Development of a Portable Tool for Screening Neuromotor Sequelae From Repetitive Low-Level Blast Exposure

Military Medicine, 2017
Blast exposure is a prevalent cause of mild traumatic brain injury (mTBI) in military personnel in combat. However, it is more common for a service member to be exposed to a low-level blast (LLB) that does not result in a clinically diagnosable mTBI. Recent research suggests that repetitive LLB exposure can result in symptomology similar to symptoms ...
Christopher K, Rhea, Nikita A, Kuznetsov, Scott E, Ross, Benjamin, Long, Jason T, Jakiela, Jason M, Bailie, Matthew A, Yanagi, F Jay, Haran, W Geoffrey, Wright, Rebecca K, Robins, Paul D, Sargent, Joshua L, Duckworth   +11 more
openaire   +2 more sources

Laminated Glass Curtain Walls and Laminated Glass Lites Subjected to Low-Level Blast Loading

Journal of Structural Engineering, 2008
Linear elastic and nonlinear elastic analytical investigations are reported for a nearly conventional, laminated glass curtain wall with split screw spline mullions subjected to low-level blast loading. Responses dynamic stresses, deflections, and accelerations of the rectangular glass lites within the curtain wall are compared to those of identical ...
David C. Weggel, Brian J. Zapata
openaire   +1 more source