Results 61 to 70 of about 24,117,299 (286)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

RGF for low-light enhancement

open access: yes, 2022
Low-light Image Enhancement with Regularized Gaussian Fields ...
Min, Chaobo, Min, C (via Mendeley Data)
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Low-Light Image Enhancement by Principal Component Analysis

open access: yesIEEE Access, 2019
Under extreme low-lighting conditions, images have low contrast, low brightness, and high noise. In this paper, we propose a principal component analysis framework to enhance low-light-level images with decomposed luminance–chrominance components.
Steffi Agino Priyanka   +2 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

A Dual-Branch Autoencoder Network for Underwater Low-Light Polarized Image Enhancement

open access: yesRemote Sensing
Underwater detection faces uncomfortable illumination conditions, and traditional optical images sensitive to intensity often cannot work well in these conditions.
Chang Xue   +4 more
doaj   +1 more source

Image resolution enhancement using dual-tree complex wavelet transform [PDF]

open access: yes, 2010
In this letter, a complex wavelet-domain image resolution enhancement algorithm based on the estimation of wavelet coefficients is proposed. The method uses a forward and inverse dual-tree complex wavelet transform (DT-CWT) to construct a high-resolution
Tjahjadi, Tardi, Çelik, Turgay
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

DEEP LEARNING-BASED LOW LIGHT IMAGE ENHANCEMENT FOR IMPROVED VISIBILITY

open access: yes, 2023
Low light conditions pose significant challenges for image capture and processing, leading to degraded image quality with reduced visibility and increased noise.
N.Baby rani, A. Joshna, B. Neelima, Ch. Varsha, G. Nikitha
core   +1 more source

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