Results 81 to 90 of about 24,117,299 (286)

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Edge and Color Information Guided High-resolution Low-light Image Enhancement Algorithm [PDF]

Jisuanji kexue
The ability of the device to capture high-resolution images poses a new challenge to image processing,and most of the existing low-light image enhancement algorithms are designed for low-resolution images,and there are problems such as unclear details ...
ZHANG Ling, LI Zhenyu
doaj   +1 more source

Low-Light Image Enhancement Using Volume-Based Subspace Analysis

IEEE Access, 2020
Low-light image enhancement is a key technique to overcome the quality degradation of photos taken under challenging illumination conditions. Even though the significant progress has been made for enhancing the poor visibility, the intrinsic noise ...
Wonjun Kim, Ryong Lee, Minwoo Park, Sang-Hwan Lee, Myung-Seok Choi   +4 more
doaj   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

FEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim, Thi Thanh Mai Tran, Nakyung Kang, Min‐Woo Lee, Mihye Lee   +4 more
wiley   +1 more source

Extreme Low-Light Image Enhancement for Surveillance Cameras Using Attention U-Net

Sensors, 2020
Low-light image enhancement is one of the most challenging tasks in computer vision, and it is actively researched and used to solve various problems. Most of the time, image processing achieves significant performance under normal lighting conditions ...
Sophy Ai, Jangwoo Kwon
doaj   +1 more source

Text in the dark: Extremely low-light text image enhancement

Extremely low-light text images pose significant challenges for scene text detection. Existing methods enhance these images using low-light image enhancement techniques before text detection.
Lin, Che-Tsung,, Ng, Chun Chet,, Nah, Wan Jun,, Long Kew, Jie,, Hsu, Pohao,, Wang, Xinyu,, Tan, Zhi Qin,, Zach, Christopher,, Lai, Shang Hong,, Seng Chan, Chee,, Lin, Che-Tsung, Wang, Xinyu, Zach, Christopher, Lai, Shang Hong, Hsu, Pohao, Tan, Zhi Qin, Nah, Wan Jun, Chan, Chee Seng, Kew, Jie Long, Ng, Chun Chet   +19 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Low-Light Image Segmentation on Edge Computing System

Sensors
Segmenting low-light images, such as images showing cracks on tunnel walls, is challenging due to limited visibility. Hence, we need to combine image brightness enhancement and a segmentation algorithm.
Sung-Chan Choi, Sung-Yeon Kim
doaj   +1 more source