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Asymptomatic Low Molecular Weight Proteinuria in Children

Pediatrics International, 1990
We reviewed the clinical features in 7 boys with asymptomatic low molecular weight proteinuria. The disease had first been reported by us in 1980. The distinctive features common to all patients were male dominance, asymptomatic proteinuria with a large amount of low molecular weight proteins, normal development and growth, normal renal function tests ...
Y, Suzuki, T, Okada
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Asymptomatic Low Molecular Weight Proteinuria: Qualitative Urinary Protein Analysis

Pediatrics International, 1992
The urinary proteins of seven patients with asymptomatic low molecular weight proteinuria (ALMP) were compared with those of Lowe syndrome and Fanconi syndrome. A characteristic electrophoretic pattern was seen in ALMP by isoelectric focusing. Two dimensional electrophoresis revealed that the ALMP proteins were localized in a more negatively charged ...
T, Watanabe, S, Takahashi
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Low Molecular Weight Proteinuria

2015
Low molecular weight (LMW) proteinurias vary widely in their microprotein composition. In general, there is little correlation between a given microprotein composition and a defined clinical disease (with the exception of the predominant beta-2-microglobulin in Wilson's disease).
Y, Manuel   +3 more
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Low concentrations of intravenous polygelines promote low‐molecular weight proteinuria

European Journal of Clinical Investigation, 2003
AbstractBackground  Previously we observed that atrial natriuretic peptide (ANP)‐induced albuminuria was accompanied by an increase in urinary excretion of the low‐molecular weight protein (LMW protein) β2‐microglobulin (β2‐m), suggesting that the albuminuria may at least partly be the result of blockade of tubular protein reabsorption. However, in our
Veldman, B.A.J.   +4 more
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Low molecular weight proteinuria in human immunodeficiency virus-infected patients

American Journal of Kidney Diseases, 1996
To determine whether human immunodeficiency virus (HIV) infection is associated with incipient tubular or glomerular defects, we determined the urinary excretion of four low molecular weight proteins (LMWP); beta2-microglobulin (U-beta2-m), cystatin C (U-cyst C), Clara cell protein (U-CC16), and retinol-binding protein (U-RBP), the markers of tubular ...
A, Kabanda   +4 more
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LOW MOLECULAR WEIGHT PROTEINURIA AND SLIGHT HYPERLIPOPROTEINEMIA IN THREE MENTALLY RETARDED BROTHERS

Acta Paediatrica, 1976
Abstract. Mental retardation in combination with proteinuria and a slight hyperlipoproteinemia was found in three brothers. The increased urinary protein excretion was dominated by albumin and the low molecular weight proteins retinol‐binding protein (RBP) and β2‐microglobulin, indicating the presence of proximal tubular dysfunction.
R, Eksmyr   +5 more
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Reversible low-molecular-weight proteinuria in patients with distal renal tubular acidosis

Pediatric Nephrology, 1990
Four patients with untreated renal tubular acidosis had a urinary excretion of low-molecular-weight (LMW) proteins which was restored to normal by alkali therapy. Hypokalaemic proximal tubular damage in untreated patients with distal renal tubular acidosis is believed to be the cause of LMW proteinuria.
T, Igarashi, H, Kawato, S, Kamoshita
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Holoprosencephaly and low molecular weight proteinuria: The human homologue of murine megalin deficiency

American Journal of Kidney Diseases, 2001
We encountered a child with holoprosencephaly, pulmonary insufficiency, absent circulating vitamin D metabolites, mild albuminuria, and urinary excretion of vitamin D-binding protein. The child displayed a phenotype highly reminiscent of that observed in mice genetically deficient for megalin, a member of the low-density lipoprotein receptor ...
D, Müller   +6 more
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Low molecular weight proteinuria in insulin-dependent diabetes.

Diabetes research (Edinburgh, Scotland), 1986
Although the protein leak of early diabetic nephropathy is said to be purely a glomerular lesion, there is still controversy as to the existence of a tubular component. We have, therefore, assessed the urine of insulin-dependent diabetics for tubular proteinuria as a feature of early diabetic nephropathy. The urine of 25 patients with increased albumin
J A, Fletcher   +5 more
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Arterial Blood Pressure Related to Degree of Albuminuria and Low-Molecular-Weight Proteinuria in IDDM

Diabetes Care, 1990
Urinary excretion of albumin and retinol-binding protein (a marker of tubular proteinuria that results from impaired proximal tubular reabsorption of lowmolecular- weight proteins) was determined in 110 insulin-dependent diabetic (IDDM) subjects. A statistically significant correlation between the urinary excretion of both proteins, in particular the ...
J, Holm, L, Hemmingsen, N V, Nielsen
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