Results 51 to 60 of about 397,115 (228)
Organic Rankine Cycle (ORC) power systems are nowadays an option for local and domestic cogeneration of heat and electric power. Very interesting are micropower systems for heat recovery from low potential (40–90 °C) waste and renewable heat sources ...
Piotr Kolasiński
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
MODELING OF THE HEAT PUMP STATION ADJUSTABLE LOOP OF AN INTERMEDIATE HEAT-TRANSFER AGENT (Part I)
There are examined equations of dynamics and statics of an adjustable intermediate loop of heat pump carbon dioxide station in this paper. Heat pump station is a part of the combined heat supply system.
Sit B.
doaj
Heat pump heating systemsand low potential heat sources
This paper focuses on the application of renewable energy resources in the form of heat pumps and their use in heating systems. As the energy prices are constantly rising, the energy management is currently a very important issue. One of the main reasons is that obtaining the primary energy sources like coal and oil is much more difficult than in the ...
Stefanco, M., Kosicanova, D.
openaire +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
This paper presents a computer model that will evaluate the performance of a thermo-chemical accumulator. The model is based on operational data such as temperatures and flow rates.
Sacha Oberweis, Tariq Al-Shemmeri
doaj +1 more source
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Natural Graphite Sheet Heat Sinks With Embedded Heat Pipes
Natural graphite sheet (NGS) is a candidate material for lightweight, high-performance heat sinks. We show that the low through-plane thermal conductivity can be mitigated by using heat pipes.
Martin Cermak +4 more
doaj +1 more source

