Results 61 to 70 of about 166,956,813 (251)

Investigation of Heat Pump Efficiency in Baltic States Using TRNSYS Simulation Tool

Environmental and Climate Technologies, 2022
A heat pump is one of the most popular energy transformation devices to provide the building with the necessary heating and cooling energy during the cold and warm seasons.
Kropas Tomas, Streckienė Giedrė, Kirsanovs Vladimirs, Dzikevics Mikelis   +3 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Research on Optimal Dispatch with Source-Load Coordination for Micro-energy Grid Based on Energy-Carbon Coupling Model

Zhongguo dianli
At present, the low-carbon dispatch of the integrated energy system focuses on the means of carbon reduction at the source side, while ignoring the low-carbon potential of the load side and the ability of carbon reduction for source-load coordination ...
Shijie XU, Bangjie HU, Liang ZHAO, Pei WANG   +3 more
doaj   +1 more source

Influence of the Thermal Energy Storage Strategy on the Performance of a Booster Heat Pump for Domestic Hot Water Production System Based on the Use of Low Temperature Heat Source

Energies, 2020
Energy recovery from a low temperature heat source using heat pump technology is becoming a popular application. The domestic hot water demand has the characteristic of being very irregular along the day, with periods in which the demand is very ...
Ximo Masip, Emilio Navarro-Peris, José M. Corberán   +2 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

MODELING OF THE HEAT PUMP STATION ADJUSTABLE LOOP OF AN INTERMEDIATE HEAT-TRANSFER AGENT (Part I)

Problems of the Regional Energetics, 2009
There are examined equations of dynamics and statics of an adjustable intermediate loop of heat pump carbon dioxide station in this paper. Heat pump station is a part of the combined heat supply system.
Sit B.
doaj  

A Review on Performance Optimization and Relevant Application Research of Heat Pump Technologies for Energy System Decarbonization

Machines
Heat pumps are core equipment for efficient low-grade thermal energy utilization and low-carbon transformation of the energy structure, offering significant energy-saving potential in building heating and industrial waste heat recovery.
Hao Huang, Bing Ni, Jing Huang, Yiqiao Li, Yali Jiang, Shengqiang Shen, Yali Guo   +6 more
doaj   +1 more source

The Influence of the Heat Source Temperature on the Multivane Expander Output Power in an Organic Rankine Cycle (ORC) System

Energies, 2015
Organic Rankine Cycle (ORC) power systems are nowadays an option for local and domestic cogeneration of heat and electric power. Very interesting are micropower systems for heat recovery from low potential (40–90 °C) waste and renewable heat sources ...
Piotr Kolasiński
doaj   +1 more source

Heat pump heating systemsand low potential heat sources

, 2016
This paper focuses on the application of renewable energy resources in the form of heat pumps and their use in heating systems. As the energy prices are constantly rising, the energy management is currently a very important issue. One of the main reasons is that obtaining the primary energy sources like coal and oil is much more difficult than in the ...
Stefanco, M., Kosicanova, D.
openaire   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source