Results 101 to 110 of about 173,284 (257)
Delta-LoRA: Fine-Tuning High-Rank Parameters with the Delta of Low-Rank Matrices
, 2023 In this paper, we present Delta-LoRA, which is a novel parameter-efficient approach to fine-tune large language models (LLMs). In contrast to LoRA and other low-rank adaptation methods such as AdaLoRA, Delta-LoRA not only updates the low-rank matrices ...
Wang, Jianan +5 more
core
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Low-rank Adaptation Method for Wav2vec2-based Fake Audio Detection
, 2023 Self-supervised speech models are a rapidly developing research topic in fake audio detection. Many pre-trained models can serve as feature extractors, learning richer and higher-level speech features.
Zhang, Xiaohui +5 more
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Low Rank Adaptation for Monocular Depth Estimation
This project integrates Low-Rank Adaptation (LoRA) into the LiteMono model for efficient monocular depth estimation across domains. By fine-tuning on the NYU-Depth-V2 dataset, we compare LoRA’s parameter-efficient performance against traditional fine ...
AlMusa, Hadi
core
Income rank and upward comparisons [PDF]
, 2008 Many studies have argued that relative income predicts individual well-being. More recently, it has been suggested that the relative rank of an individual’s income, rather than how that income compares to a mean or reference income, is important.
Boyce, Christopher J. +1 more
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
ASLoRA: Adaptive Sharing Low-Rank Adaptation Across Layers
CoRRAs large language models (LLMs) grow in size, traditional full fine-tuning becomes increasingly impractical due to its high computational and storage costs. Although popular parameter-efficient fine-tuning methods, such as LoRA, have significantly reduced the number of tunable parameters, there is still room for further optimization.
Junyan Hu +6 more
openaire +2 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source