Results 31 to 40 of about 173,284 (257)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Mitigating Forgetting in Low Rank Adaptation

open access: yesCoRR
Parameter-efficient fine-tuning methods, such as Low-Rank Adaptation (LoRA), enable fast specialization of large pre-trained models to different downstream applications. However, this process often leads to catastrophic forgetting of the model's prior domain knowledge.
Joanna Sliwa 0002   +3 more
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Supporting evidence-based adaptation decision-making in South Australia: a synthesis of climate change adaptation research [PDF]

open access: yes, 2013
This research synthesis provides policy-makers and practitioners with an understanding of the building blocks for effective adaptation decision-making, as evidenced through the NCCARF research program.
Laura Cacho   +2 more
core  

Higher-harmonic adaptation and the detection of squarewave gratings [PDF]

open access: yes, 1987
Adaptation to a high contrast sinewave grating of 1 c/deg spatial frequency causes a large increase in the contrast threshold for a 1 c/deg test grating, but fails to raise the threshold for a squarewave grating of 0.33 c/deg, although the sensitivity of
Magnussen, S.   +3 more
core   +1 more source

Towards Symmetric Low-Rank Adapters

open access: yesCoRR
Colorai ...
Tales Panoutsos   +2 more
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Supporting evidence-based adaptation decision-making in Western Australia: a synthesis of climate change adaptation research [PDF]

open access: yes, 2013
This research synthesis provides policy-makers and practitioners with an understanding of the building blocks for effective adaptation decision-making, as evidenced through the NCCARF research program.
Laura Cacho   +2 more
core  

Low-rank Adaptation of Large Language Model Rescoring for Parameter-Efficient Speech Recognition

open access: yes, 2023
We propose a neural language modeling system based on low-rank adaptation (LoRA) for speech recognition output rescoring. Although pretrained language models (LMs) like BERT have shown superior performance in second-pass rescoring, the high computational
Liu, Yi-Chieh   +17 more
core   +1 more source

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