Results 121 to 130 of about 11,850,628 (306)

Multi-Task ConvMixer Networks with Triplet Attention for Low-Resource Keyword Spotting

Tsinghua Science and Technology
Customized keyword spotting needs to adapt quickly to small user samples. Current methods primarily solve the problem under moderate noise conditions. Recent work increases the level of difficulty in detecting keywords by introducing keyword interference.
Alexander Rogath Kivaisi, Qingjie Zhao, Yuanbing Zou   +2 more
doaj   +1 more source

Institute of Natural Resource Sustainability 2010 Annual Report [PDF]

, 2011
not peer reviewedSubmitted by Susan Braxton (braxton@illinois.edu) on 2011-11-09T16:01:09Z No. of bitstreams: 1 annual-rept-fy10.pdf: 2579510 bytes, checksum: 1109fc3026377cc8055a3aa305b4f370 (MD5)Made available in DSpace on 2011-11-09T16:01:09Z (GMT ...
Institute of Natural Resource Sustainability
core  

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Flow and heat transfer characteristics of seawater falling-film evaporation on horizontal tubes

Desalination and Water Treatment
Owing to their excellent heat transfer performance, falling film evaporators are widely employed in desalination and related fields. This study develops a three-dimensional, two-tube model based on the Volume of Fluid method to investigate the effects of
Liu Hua, Wang Tianye, Zhao Jieyu, Dong Defan, Feng Xin   +4 more
doaj   +1 more source

Institute of Natural Resource Sustainability 2008-2009 Annual Report [PDF]

, 2009
not peer reviewedSubmitted by Susan Braxton (braxton@illinois.edu) on 2011-11-09T15:58:39Z No. of bitstreams: 1 annual-rept-fy09.pdf: 2063631 bytes, checksum: c9de98955cb7abde12830c64339933ff (MD5)Made available in DSpace on 2011-11-09T15:58:39Z (GMT ...
Institute of Natural Resource Sustainability
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Era- and Genre-Specific Stop Word Lists for Low-Resource Computational Research: A Classical Latin 'Exemplum'

Journal of Open Humanities Data
In this data paper, we argue that computational researchers—particularly those working in low-resource contexts—should consult with linguistic specialists to create targeted stop lists developed with specific eras, genres, authors, or contexts in mind ...
Rachel E. Dubit, Annie K. Lamar
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source