Results 101 to 110 of about 1,127,739 (284)
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
A Low-resource Approach to SemTab 2022. [PDF]
, 2023 Mapping tabular data to a Knowledge Graph is a common task that often involves the use of considerable resources in terms of disk space, system memory and processing power. This paper introduces a barebones system that needs only modest computer hardware and only relies on Python, yet still achieves 77.0% F1 and 84.6% F1 on the SemTab 2022 Round 1 CTA ...
openaire +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
A Clause-Based Data Augmentation Method for Low-Resource Neural Machine Translation
IEEE AccessTransformer-based neural machine translation (NMT) systems have achieved remarkable success with high-resource bilingual corpora. However, their performance deteriorates significantly in low-resource environments due to the scarcity of training data.
Fuxue Li +3 more
doaj +1 more source
Machine Translation of Low-Resource Spoken Dialects: Strategies for Normalizing Swiss German
, 2018 The goal of this work is to design a machine translation (MT) system for a low-resource family of dialects, collectively known as Swiss German, which are widely spoken in Switzerland but seldom written.
Baeriswyl, Michael +3 more
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Flow and heat transfer characteristics of seawater falling-film evaporation on horizontal tubes
Desalination and Water TreatmentOwing to their excellent heat transfer performance, falling film evaporators are widely employed in desalination and related fields. This study develops a three-dimensional, two-tube model based on the Volume of Fluid method to investigate the effects of
Liu Hua +4 more
doaj +1 more source