Results 51 to 60 of about 1,389,721 (276)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Natural Language Processing Tools for Romanian – Going Beyond a Low-Resource Language.

open access: yesInteraction Design and Architecture(s)
Advances in Natural Language Processing bring innovative instruments to the educational field to improve the quality of the didactic process by addressing challenges like language barriers and creating personalized learning experiences.
Melania Nitu, Mihai Dascalu
doaj   +1 more source

Twi Machine Translation

open access: yesBig Data and Cognitive Computing, 2023
French is a strategically and economically important language in the regions where the African language Twi is spoken. However, only a very small proportion of Twi speakers in Ghana speak French.
Frederick Gyasi, Tim Schlippe
doaj   +1 more source

Advances in Low-Resource and Endangered Languages

open access: yesProceedings of the Workshop on Computational Methods for Endangered Languages, 2021
This paper reports on the approaches and results for the collection, analysis, and processing of low-resource and endangered languages carried out under the Low-Resource Languages for Emergent Incidents (LORELEI) Program1. LORELEI was a multi-year research and development program designed to discover new methods of quickly ramping up human language ...
Evelyne Tzoukermann   +3 more
openaire   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

A Parallel Corpus-Based Approach to the Crime Event Extraction for Low-Resource Languages

open access: yesIEEE Access, 2023
These days, a lot of crime-related events take place all over the world. Most of them are reported in news portals and social media. Crime-related event extraction from the published texts can allow monitoring, analysis, and comparison of police or ...
Nina Khairova   +4 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Model Transfer for Tagging Low-resource Languages using a Bilingual Dictionary

open access: yes, 2017
Cross-lingual model transfer is a compelling and popular method for predicting annotations in a low-resource language, whereby parallel corpora provide a bridge to a high-resource language and its associated annotated corpora.
Cohn, Trevor, Fang, Meng
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Development of Dialogue Management System for Banking Services

open access: yesApplied Sciences, 2021
Rapid increase in conversational AI and user chat data lead to intensive development of dialogue management systems (DMS) for various industries. Yet, for low-resource languages, such as Azerbaijani, very little research has been conducted.
Samir Rustamov   +2 more
doaj   +1 more source

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