Results 121 to 130 of about 13,073,421 (310)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Operational challenges and collaborative solutions in radiology image interpretation: perspectives from imaging departments in a low‐resource setting

Journal of Medical Radiation Sciences
Introduction Medical imaging's critical role in diagnosis requires prompt and precise image interpretation. Numerous radiology departments, especially in low‐resourced settings, encounter challenges such as a shortage of radiologists in their operational
Abel Karera, Florence Davidson, Penelope Engel‐Hills   +2 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

The Economics of HIV/AIDS in Low-Income Countries: The Case for Prevention [PDF]

There are two approaches to reducing the burden of sickness and death associated with HIV/AIDS: treatment and prevention. With limited resources, should the focus be on prevention or treatment? I discuss the range of prevention and treatment alternatives,
David Canning
core  

Findings of the LoResMT 2020 shared task on zero-shot for low-resource languages

, 2020
This paper presents the findings of the LoResMT 2020 Shared Task on zero-shot translation for low resource languages. This task was organised as part of the 3rd Workshop on Technologies for MT of Low Resource Languages (LoResMT) at AACL-IJCNLP 2020.
Ojha, Atul Kr., Liu, Chao-Hong, Malykh, Valentin, Karakanta, Alina   +3 more
core   +1 more source

Telepathology in Low Resource African Settings [PDF]

Frontiers in Public Health, 2019
Nnamdi Orah, Olorunda Rotimi, Olorunda Rotimi   +2 more
openaire   +3 more sources

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Postpartum hemorrhage: incidence, risk factors, and outcomes in a low-resource setting

, 2016
Solwayo Ngwenya1–3 1Department of Obstetrics and Gynaecology, Mpilo Central Hospital, Bulawayo, Zimbabwe; 2Royal Women’s Clinic, Bulawayo, Zimbabwe; 3Medical School, National University of Science and Technology, Matabeleland, Zimbabwe ...
Ngwenya S, Ngwenya, Solwayo
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Management of cervical cancer in pregnancy in a low resource setting: a rare case report

Background Cervical cancer in pregnancy is a rare event. Diagnosis and management of cervical cancer in pregnancy is complicated and challenging in a low resource setting.
Rojna Rai, Nishal Chhetri, Sangay Tshering, Namkha Dorji, Sonam Dechen   +4 more
core   +1 more source