Results 131 to 140 of about 13,073,421 (310)

Evaluation of commercial point-of-care glucometers for detection and monitoring of neonatal hypoglycemia in resource-constrained settings

BMC Pediatrics
Background Accurate identification and treatment of hypoglycemia or low blood glucose is important for neonates, especially premature, small for gestational age, and intra-uterine growth restricted (“small and sick”) newborns. Existing point-of-care (POC)
Meaghan Bond, Elizabeth Asma, Joseph Peterson, Lauren Oparah, Millicent Alooh, Danica Kumara, Z. Maria Oden, Chinyere Ezeaka, Elizabeth Molyneux, Rebecca Richards-Kortum   +9 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Peritonitis following caesarean section in a low-resource setting [PDF]

Maternal sepsis is the third-leading cause of maternal death worldwide, and caesarean section is an important risk factor for developing maternal infection.
Mtaya, Gabriel, Riches, Jennifer, Onrust, Marthe, Phiri, Priscilla   +3 more
core   +1 more source

Ujuzi Practical Pearl/Perle Pratique

African Journal of Emergency Medicine, 2012
Mark Bisanzo
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

A wireless semi-wearable sensor for assessment of gut function in low-resource settings

Environmental enteric dysfunction (EED) is a subclinical disorder of intestinal function common in tropical countries and settings of poverty and economic disadvantage.
Sanchez, Elena M, Thompson, Alex J, Gan, Jonathan, Mwiinga, M, Optics and Biophotonics in Low-Resource Settings X, Mandal, N, Avery, James, Banda, Rose, Chen, Qian, Gan, J, Chen, Q, Mandal, Nilanjan, Sanchez, EM, Thompson, AJ, Avery, J, Kelly, Paul, Mwiinga, Mulima, Banda, R, Kelly, P   +18 more
core   +1 more source

Small batch sizes improve training of low-resource neural MT

, 2022
We study the role of an essential hyperparameter that governs the training of Transformers for neural machine translation in a low-resource setting: the batch size.
Atrio, Alex R., Popescu-Belis, Andrei
core  

Breastfeeding in low-resource settings: Not a “small matter”

PLOS Medicine, 2018
Despite its clear biological benefits, many infants globally do not receive exclusive breastfeeding. In a Guest Editorial, Lars Åke Persson discusses what is needed to make breastfeeding the social norm.
openaire   +3 more sources

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source