Results 61 to 70 of about 1,835,297 (301)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Seismic Safety Assessment of Existing Low-rise RC Buildings with Rapid Visual Screenings and Preliminary Evaluation Methods

open access: yesASEAN Journal on Science and Technology for Development, 2021
Mandalay, the second largest city in Myanmar, is situated near the Sagaing Fault (the major fault in Myanmar). In the Mandalay region, the number of low-rise buildings is much greater than that of high-rise buildings.
Moe Myat Myat Aung, Mya Nan Aye
doaj   +1 more source

Creating nuclear spin entanglement using an optical degree of freedom [PDF]

open access: yes, 2014
Funding: Marie Curie Early Stage Training network QIPEST (Grant No. MESTCT-2005-020505), the EPSRC through QIP IRC (Grant Nos. GR/S82176/01 and GR/S15808/01), the National Research Foundation and Ministry of Education, Singapore, the DAAD (German ...
Gauger, Erik M.   +2 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Indoor Fire Simulation in Low-Rise Teaching Buildings Based on BIM–FDS

open access: yesFire, 2023
School buildings gather a large number of underage students, and the disastrous consequences of fire in such buildings are very serious, which is one of the key concerns of society in fire prevention and control.
Mengkai Liu, Guoquan Wang
doaj   +1 more source

Floor-level premiums in high-rise and low-rise buildings [PDF]

open access: yes, 2006
This paper examines a unique feature of multi-storey buildings – floor-level premiums. Floor-level premiums refer to the price paid for the vertical location of a flat, measured by its floor level.
Chau, KW, Cheung, KC, Wong, SK, Yau, Y
core  

A Holistic Approach to Log Data Analysis in High-Performance Computing Systems: The Case of IBM Blue Gene/Q [PDF]

open access: yes, 2015
The complexity and cost of managing high-performance computing infrastructures are on the rise. Automating management and repair through predictive models to minimize human interventions is an attempt to increase system availability and contain these ...
B Javadi   +3 more
core   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Multi-Objective Optimisation of Skylight Design Parameters for a Low-rise Building in the Tropics

open access: yesInternational Journal of Technology
Skylight is an effective strategy for maximising daylight penetration while minimising electrical lighting energy demand in buildings. However, in tropical climate regions, skylight can be problematic due to the risk of excessive sunlight. This study
Dinta Wijaya   +2 more
doaj   +1 more source

Standardisation Of Precast Concrete Members For Low-Rise Residential Framed Building [PDF]

open access: yes, 2002
Precast concrete technology has become an emerging trend in Malaysian Construction Industry. Hence, there is a niche in developing a set of standardised and optimised precast concrete elements as well as connections for a speedy, affordably and better
Heng, Chiang Chew
core  

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