Results 91 to 100 of about 92,105 (300)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Buildings for low energy air conditioning

, 1998
Over half of global warming is thought to be attributable to the burning of fossil fuelsand slightly less than half of this is due to conditioning the environment withinbuildings.
Oreszczyn, T
core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Multidimensional Evaluation Framework and Classification Strategy for Low-Carbon Technologies in Office Buildings

Buildings
The global climate crisis has driven unprecedented agreements among nations on carbon mitigation. With China’s commitment to carbon peaking and carbon neutrality targets, the building sector has emerged as a critical focus for emission reduction ...
Hongjiang Liu, Yuan Song, Yawei Du, Tao Feng, Zhihou Yang   +4 more
doaj   +1 more source

Strategies for low carbon buildings : Assessment of design options and the translation of design intent into performance in practice

, 2013
To deliver low carbon buildings requires: a) Performance assessment and option appraisal; b) Industry process to translate selected options into low carbon performance in practice.
Tuohy, Paul Gerard, Clarke, Joe, Johnstone, Cameron   +2 more
core  

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

LCA of Re-Membrane for buildings/tunnels

In the Re-Membrane project, the project participants have developed and manufactured plastic film for buildings and tunnel membranes including recycled plastic raw material. RISE has performed testing the products for long-term applications.
Brunklaus, Birgit
core   +1 more source

The Influence of High-Rise Buildings on Pedestrian-Level Wind in Surrounding Street Canyons in an Urban Renewal Project

, 2020
The pedestrian wind environment in a street canyon is affected by a multitude of factors, including the height and geometric shape of the surrounding buildings, the street width, the wind direction, and speed.
Chun-Ta Tzeng, Tzu-Ling Huang, Chi-Ming Lai, Chien-Yuan Kuo   +3 more
core   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Dynamic Analysis of Low-Rise Buildings on Microcomputers

Computer-Aided Civil and Infrastructure Engineering, 1987
An analytical model for dynamic response analysis of low-rise steel frame buildings on microcomputers is described. The model consists of an assemblage of planar frames with either braced or moment resisting connections. All but the frame lateral degrees of freedom are removed using static condensation prior to assemblage of the overall model.
BARRY J. GOODNO, MARK C. STREIT
openaire   +1 more source