Results 101 to 110 of about 663,749 (311)

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Measuring the Long-Term Regional Benefits of Salinity Reduction

open access: yes
Approaches for evaluating salinity management benefits are generalized and extended to incorporate consideration of desalination and long-term changes in salinity concentration and water use patterns.
Characklis, Gregory W.   +2 more
core  

Amelioration of salinity toxicity in South African crop plants with special reference to maize

open access: yes, 1992
Bibliography: leaves 87-101.The effects of ammonium and nitrate nutrition on potassium uptake, photosynthetic gas exchange and growth responses to salinity stress (80 mM) together with the ameliorative roles of three ranges of calcium concentrations (2.5
Tshivhandekano, Thivhulawi Robert
core  

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Farmers' perceptions on salinity and sodicity: A case study into farmers' knowledge of salinity and sodicity, and their strategies and practices to deal with salinity and sodicity in their farm systems [PDF]

open access: yes
Farmer managed irrigation systems / Salinity / Sodic soils / Sustainable agriculture / Farmers' attitudes / Case studies / Water quality / Pakistan / Punjab / Chishtian Sub ...
Kielen, N.
core  

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

AN ECONOMIC EVALUATION OF THE COLORADO RIVER BASIN SALINITY CONTROL PROGRAM

open access: yes
Dissolved salts (salinity) adversely affect numerous urban and agricultural users of Colorado River water in California and Arizona. Congress in 1974 authorized a major salinity control program.
Young, Robert A., Gardner, Richard L.
core  

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

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