Results 71 to 80 of about 963,853 (358)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Enhanced Infrared Image Processing for Impacted Carbon/Glass Fiber-Reinforced Composite Evaluation

Sensors, 2017
In this paper, an infrared pre-processing modality is presented. Different from a signal smoothing modality which only uses a polynomial fitting as the pre-processing method, the presented modality instead takes into account the low-order derivatives to ...
Hai Zhang, Nicolas P. Avdelidis, Ahmad Osman, Clemente Ibarra-Castanedo, Stefano Sfarra, Henrique Fernandes, Theodore E. Matikas, Xavier P. V. Maldague   +7 more
doaj   +1 more source

Modelling Low Velocity Impact on Structural Composites

IOP Conference Series: Materials Science and Engineering, 2020
Abstract Insertion of composite materials into next generation vehicles requires an understanding of their response over the range of relevant loading conditions encountered in the field. This paper focuses on modelling the low velocity, high energy impact on structural composite materials.
M Yeager, S E Boyd, J M Staniszewski, B A Patterson, D B Knorr, T A Bogetti   +5 more
openaire   +1 more source

Simulations of vibrated granular medium with impact velocity dependent restitution coefficient [PDF]

, 2005
We report numerical simulations of strongly vibrated granular materials designed to mimic recent experiments performed both in presence or absence of gravity.
Falcon, Eric, Mcnamara, Sean
core   +4 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Characterization of Low-Velocity Impact Damage in Asymmetric Composite Shells [PDF]

Journal of Applied and Computational Mechanics
Based on numerical modelling, this study investigates asymmetric semicylindrical composite laminate shells' damage characteristics under low-velocity impact loads.
Luis Ferreira, Carlos Coelho, Paulo Reis
doaj   +1 more source

Development of methologies to study the damage tolerance of aeronautical and aerospace composite structures [PDF]

, 2008
Mechanics of Advanced Materials research group (Department of Continuum Mechanics and Structural Analysis) of the University Carlos III of Madrid (Spain) offers their experience in the analysis and modelization of high and low velocity impact behaviour ...
Barbero Pozuelo, Enrique, Sánchez Sáez, Sonia   +1 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

A Novel Spring-Actuated Low-Velocity Impact Testing Setup

Applied System Innovation
Evaluating the behavior of materials and their response under low-velocity dynamic impact (less than 30 m/s) is a challenging task in various industries.
Mesut Kucuk, Moheldeen Hejazi, Ali Sari
doaj   +1 more source

Low velocity impact analysis with NASTRAN [PDF]

A nonlinear elastic force-displacement relationship is used to calculate the transient impact force and local deformation at the point of contact between impactor and target.
Aiello, Robert A., Grady, Joseph E., Trowbridge, Daniel A.   +2 more
core   +1 more source