Results 191 to 200 of about 2,954 (261)

Living with the Unknown: Intolerance of Uncertainty in Parkinson's Disease

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) is marked by pervasive uncertainty due to fluctuating motor and non‐motor symptoms, variable treatment response, and an unpredictable clinical course. Intolerance of uncertainty (IU), a tendency to perceive ambiguity as threatening and respond with worry, avoidance, or decisional paralysis, may be ...
Bradley McDaniels   +3 more
wiley   +1 more source

Effect of COMT and UGT1A Variants on Clinical Response to Opicapone in Parkinson's Disease

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) is the second most common neurodegenerative disease. Symptomatic treatment is based on dopaminergic replacement. With disease progression, the initial benefit of levodopa becomes inconsistent, and motor complications emerge.
Elena Ojeda‐Lepe   +15 more
wiley   +1 more source

R&D Organization and Corporate Social Responsibility Specialization

open access: yesManagerial and Decision Economics, EarlyView.
ABSTRACT In this paper, we examine whether the scope of corporate social responsibility (CSR) should be broad or narrow. A broad scope covers both production and R&D investment decisions, while a narrow scope applies only to production decisions. We show that both firms' choices and the government's preferences depend on the level of CSR concern and on
Quan Dong   +2 more
wiley   +1 more source

Demand‐Driven Mergers: Advertising, Differentiation, and Welfare

open access: yesManagerial and Decision Economics, EarlyView.
ABSTRACT We consider mergers that induce demand changes. We study the firms' incentives to submit a merger request and the competition authority's decision to approve the request. We show that merger‐induced demand changes help expand settings where the interests of firms and competition authority align, whereas contexts where their interests are ...
Felix Munoz‐Garcia   +2 more
wiley   +1 more source

Apathy in Lewy Body Disorders: A Position Paper

open access: yesMovement Disorders, EarlyView.
Abstract Apathy is one of the most prevalent and disabling non‐motor symptoms in Parkinson's disease (PD) and dementia with Lewy bodies (DLB), collectively referred to as Lewy body disorders (LBDs). It is associated with reduced quality of life, accelerated cognitive decline, increased caregiver burden, and poorer functional outcomes, yet remains ...
Jaime Kulisevsky   +12 more
wiley   +1 more source

Real‐Time Fractional Control of an Electrohydraulic System Using Low‐Cost Technology

open access: yesInternational Journal of Mechanical System Dynamics, EarlyView.
ABSTRACT Advances in control methods for electrohydraulic systems (EHS) improve performance by addressing nonlinearities and unknown parameters, although most studies are limited to numerical simulations. Furthermore, research with experimental validation often relies on high‐performance computing equipment, specialized data acquisition cards, and ...
Edgar H. Robles‐Sauceda   +5 more
wiley   +1 more source

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