Results 21 to 30 of about 84,951 (308)

Effects of Preoperative Radiotherapy on Long-Term Bowel Function in Patients With Rectal Cancer Treated With Anterior Resection: A Systematic Review and Meta-analysis

Technology in Cancer Research & Treatment, 2022
Background: Anterior resection is a common surgical approach used in rectal cancer surgery; however, this procedure is known to cause bowel injury and dysfunction. Neoadjuvant therapy is widely used in patients with locally advanced rectal cancer.
Zongyu Liang MM, Zhaojun Zhang MM, Deqing Wu MD, Chengzhi Huang MM, Xin Chen MM, Weixian Hu MM, Junjiang Wang MD, Xingyu Feng MD, Xueqing Yao PhD, MD   +8 more
doaj   +1 more source

Robotic Low Anterior Resection and TAH+BSO with Transvaginal NOSE

Turkish Journal of Colorectal Disease, 2021
In the last century, laparoscopic interventions have been developed to minimize the somatic and phsiological effects of surgery. Laparoscopic approaches have become frequently used in colorectal surgery as well.
Neşet Köksal, Ömer Faruk Özkan, Ethem Ünal, İsmail Kabak, Muhammed Taha Demirpolat, Gürkan Kıran   +5 more
doaj   +1 more source

Low anterior resection syndrome and methods of its assessment (literature review)

Южно-Российский онкологический журнал, 2023
Low anterior resection syndrome is a common problem due to the increased incidence of rectal cancer and the high incidence of anorectal dysfunction during sphincter-preserving surgical interventions.
O. K. Bondarenko, Yu. A. Gevorkyan, N. V. Soldatkina, M. A. Gusareva, N. G. Kosheleva, A. A. Solntseva, M. N. Duritsky, D. A. Savchenko   +7 more
doaj   +1 more source

A Systematic Review of Evidence on the Clinical Effectiveness of Surveillance Imaging in Children With Medulloblastoma and Ependymoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd, Melissa Taylor, Helen Fulbright, Bob Phillips   +3 more
wiley   +1 more source

Low anterior rectal resection; the impact of anastomotic fistula on incidence and severity of low anterior resection syndrome

Journal of Mind and Medical Sciences
Objectives. Low anterior resection is a common surgical procedure for rectal cancer, but it is associated with a distressing complication known as Low Anterior Resection Syndrome (LARS).
Giorgiana Coțofană Graure, Cecil Mirea, Silviu Daniel Preda, Ștefan Pătrașcu, Tiberiu Stefanita Tenea-Cojan, Adina Turcu-Stiolica, Alexandru Munteanu, Vlad Padureanu, Dragos Margaritescu, Sandu Ramboiu, Dan Cartu, Valeriu Șurlin, Petre Radu   +12 more
doaj   +1 more source

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

Radiotherapy as a potential risk factor for delayed anastomotic leakage after rectal surgery: a meta-analysis

BMC Surgery
Background Radiotherapy is a well-recognized risk factor of acute leakage after colorectal surgery. However, its relationship with delayed leakage remains unclear.
Jau-Jie You, Abe Fingerhut, Yi-Chang Chen, William Tzu-Liang Chen, Ming-Yin Shen   +4 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Analysis of the correlation between defunctioning stoma and postoperative low anterior resection syndrome in rectal cancer: a prospective cohort study

BMC Gastroenterology
Background To evaluate the effect of stoma-related factors (stoma or no stoma, stoma type, and stoma reversal time) on the occurrence of low anterior resection syndrome (LARS), a highly prevalent condition that can develop after anal sphincter-sparing ...
Yuhan Qi, Zhiyuan Zhang, Qianru Yang, Li Li, Xiaodong Wang, Mingjun Huang   +5 more
doaj   +1 more source