Results 231 to 240 of about 55,225 (289)

Risk Factors for Airway Infantile Hemangioma

Acta Paediatrica, EarlyView.
ABSTRACT Aim An infantile hemangioma (IH) affecting the airway is rare. Identifying infants at risk for an airway IH is crucial to avoid potential airway compromise. Our objective was to identify risk factors for an airway IH and to study its incidence and treatments.
Eeva Castrén, Päivi Salminen, Kristiina Kyrklund   +2 more
wiley   +1 more source

High output stoma after surgery for rectal cancer - a risk factor for low anterior resection syndrome? [PDF]

BMC Gastroenterol
Zhang X, Meng Q, Du J, Tian Z, Li Y, Yu B, Niu W.   +6 more
europepmc   +1 more source

Score assessment and treatment in patients presenting with low anterior resection syndrome after sphincter-sparing rectal cancer surgery. [PDF]

Int J Colorectal Dis
Sguinzi R, Fiechter J, Bafumi L, Gremaud B, Geng B, Janiak P, Bühler L, Egger B.   +7 more
europepmc   +1 more source

The impact of Low-Anterior Resection Syndrome (LARS) on the Quality of Life in Rectal Cancer Survivors: a Narrative Review. [PDF]

Maedica (Bucur)
Stanculea F, Ungureanu CO, Roca D, Ginghina O, Mihailov R, Grama F, Iordache N.   +6 more
europepmc   +1 more source

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source

Electroacupuncture versus sham electroacupuncture in treating low anterior resection syndrome after rectal cancer surgery: Study protocol for a randomized controlled trial. [PDF]

PLoS One
Wang ZY, Shi GX, Wang Y, Pei W, Yang YC, Yang JW, Wei XY, Jia JY, Tu JF, Liu CZ.   +9 more
europepmc   +1 more source

Human intestinal and multivisceral transplantation [PDF]

, 1994
Abu-Elmagd, K, Cillo, U, Fung, JJ, Furukawa, H, Marino, IR, Scotti-Foglieni, CL, Starzl, TE, Todo, S, Tzakis, A   +8 more
core  

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Physiological Basis of Sex Differences in Human Performance and Exercise‐Associated Pathology

Clinical Endocrinology, EarlyView.
ABSTRACT The presence of sex differences in human physical performance is well‐established and shaped by distinct endocrine, anatomical and physiological mechanisms. Despite sustained advances, our understanding of how inherent biological factors drive variations in exercise capacity and related pathologies is still developing.
David A. Holdsworth, Thomas J. O'Leary, Craig L. Doig, Natalie Taylor, Jasminder Dosanjh, David R. Woods, Michael J. Stacey, Robert M. Gifford   +7 more
wiley   +1 more source

Homozygous Loss‐of‐Function Variant in SLC20A1 Coding for Ubiquitous Phosphate Transporter PiT1 Is Associated With Multiple Developmental Abnormalities

Clinical Genetics, EarlyView.
Biallelic SLC20A1 loss‐of‐function variant causes a previously unrecognized multisystem developmental disorder. We report the first homozygous case presenting with tetralogy of Fallot, renal agenesis, polydactyly, and growth impairment. Transcriptome analysis of patient‐derived fibroblasts suggests significant dysregulation of pathways critical for ...
Eugénie Koumakis, Céline Huber, Wendy Chung, Christine Leroy, Pauline Parisot, Regis Gaudin, Mohamad Zaidan, Valérie Cormier‐Daire, Gérard Friedlander, Yoel Hirsch   +9 more
wiley   +1 more source