Results 1 to 10 of about 10,491,704 (178)

Management of Low Anterior Resection Syndrome (LARS) Following Resection for Rectal Cancer [PDF]

Cancers, 2023
Introduction: A total of 60–80% of patients undergoing rectal resection (mostly as a treatment for rectal cancer) suffer from a variety of partly severe functional problems despite preservation of the anal sphincter. These patients are summarized under the term low anterior resection syndrome (LARS).
Harald Rosen, Christian Šebesta
exaly   +5 more sources

Risk factors for Low Anterior Resection Syndrome (LARS) in patients undergoing laparoscopic surgery for rectal cancer. [PDF]

Surg Endosc, 2022
AbstractBackgroundTotal mesorectal excision (TME) represents the “gold standard” of rectal cancer surgery. In locally advanced lesions neoadjuvant treatments (e.g. radiotherapy-nRT, radio chemotherapy-cnRT) have been shown to improve TME oncological results, reducing local recurrences rate.
Nicotera A, Falletto E, Arezzo A, Mistrangelo M, Passera R, Morino M.   +5 more
europepmc   +7 more sources

Validation of the Turkish translation of the low anterior resection syndrome (LARS) score

Techniques in Coloproctology, 2023
Long-term bowel dysfunction after resection for rectal cancer, known as low anterior resection syndrome (LARS), is observed in many patients. The LARS score was developed to assess this syndrome and its impact on the quality of life in Danish patients. Recently versions in English and many other languages have been validated.
Selman Sokmen, Cihangir Akyol, Thérèse Juul   +2 more
exaly   +8 more sources

Low Anterior Resection Syndrome (LARS) after Surgery for Rectal Cancer: An Inevitable Price to Pay for Survival, or a Preventable Complication? [PDF]

Journal of Clinical Medicine, 2023
Background: Rectal cancer is frequent and often treated with sphincter-saving procedures that may cause LARS, a syndrome characterized by symptoms of bowel disfunction that may severely affect quality of life. LARS is common, but its pathogenesis is mostly unknown.
Alessandro Coppola, Mattia Falchetto Osti, Giovanni Maria Garbarino   +2 more
exaly   +5 more sources

Bidirectional longitudinal associations between low anterior resection syndrome and stigma in patients with postoperative LARS: a cross-lagged panel study [PDF]

Frontiers in Public Health
ObjectiveTo investigate the bidirectional longitudinal associations between low anterior resection syndrome (LARS) and stigma among patients with postoperative LARS following sphincter-preserving surgery for rectal cancer.MethodsA total of 201 patients ...
Xiangdong Hu, Qiushi Yin, Mei Cao, Changcui Liang, Hui Yang   +4 more
doaj   +3 more sources

Validation of Urdu Version of the Low Anterior Resection Syndrome (LARS) Score. [PDF]

Indian J Surg Oncol, 2023
Patients subjected to low anterior resection for rectal cancers experience a constellation of symptoms of disordered bowel function which leads to a detriment in the quality of life. The LAR syndrome (LARS) score is a self-administered questionnaire to identify and assess disordered bowel function after resective surgery.
Banday I, Malik AA, Khan MA, Parray F, Wani RA, Banday M, Zahoor H.   +6 more
europepmc   +3 more sources

Low anterior resection syndrome (LARS) and quality of life after colectomy

International Journal of Colorectal Disease, 2023
Clinical experience shows complaints similar to LARS not only after rectal surgery, but even after other types of colorectal surgery. Our aim was to investigate the occurrence of LARS after several types of colorectal surgery and its impact on quality of life.We included adult patients who underwent colorectal surgery at our centre from January 2016 ...
Niels Komen, Sylvie van den Broeck, Juul Meurs   +2 more
exaly   +4 more sources

Low anterior resection syndrome after sphincter-preserving surgery for rectal cancer: predictive factors and impact on perceived functional satisfaction [PDF]

Discover Oncology
Background Sphincter-preserving surgery (SPS) for rectal cancer poses challenges in balancing oncological safety with postoperative function. This study aimed to evaluate the prevalence and determinants of Low Anterior Resection Syndrome (LARS) and to ...
B. Suraga, Sandeep P. Nayak, Bharath Gangadhara, Sreekanth Reddy, Ameenuddin Khan, Devaprasad Munisiddaiah, P. Vinodhini, Vidyashri H Biral, Sriram S. Janakiraman, Keerthi Ranganathan   +9 more
doaj   +2 more sources

A systematic review of preoperative radiological factors associated with the development of low anterior resection syndrome (LARS). [PDF]

Updates Surg
Abstract The aim of this systematic review is to summarise the available evidence for radiological changes associated with postoperative low anterior resection syndrome (LARS). A literature search was undertaken for all studies focusing on preoperative radiological predictors of postoperative LARS.
Gravante G, De Simone V, Gallo G, Currò G.   +3 more
europepmc   +3 more sources

Predictive Risk Factors for Low Anterior Resection Syndrome (LARS) in Rectal Cancer-An Observational Cohort Study. [PDF]

J Clin Med
Background/Objectives: The improved long-term survival of rectal cancer patients has led to a major increase in the prevalence of functional complications. Understanding which patients are prone to develop major LARS is important for their preoperative counselling and follow-up. Herein, we aimed to assess the risk factors for LARS.
Lunca S, Morarasu S, Osman C, Shatarat FA, Gramada T, Razniceanu M, Buzemurga M, Baltig E, Zaharia R, Ong WL, Dimofte GM.   +10 more
europepmc   +3 more sources