Percutaneous tibial nerve stimulation in patients with severe low anterior resection syndrome: randomized clinical trial [PDF]
, 2021 Treatment of low anterior resection syndrome (LARS) is challenging. Percutaneous tibial nerve stimulation (PTNS) can improve select bowel disorders.
Alberti, P +9 more
core +1 more source
Hepatology, EarlyView., 2022 Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.
Shannon M. Vandriel +93 more
wiley +1 more source
Predictive Risk Factors for Low Anterior Resection Syndrome (LARS) in Rectal Cancer-An Observational Cohort Study. [PDF]
J Clin MedBackground/Objectives: The improved long-term survival of rectal cancer patients has led to a major increase in the prevalence of functional complications. Understanding which patients are prone to develop major LARS is important for their preoperative counselling and follow-up. Herein, we aimed to assess the risk factors for LARS.
Lunca S +10 more
europepmc +3 more sources
The Clinical Relevance of the Rectosigmoid Brake in Surgical Disorders and Therapies: A Systematic Review of Colonic Manometry Studies. [PDF]
Neurogastroenterol MotilColonic motility mapping reveals a meal‐induced rectosigmoid brake in healthy individuals that is disrupted, disorganized, or exaggerated following surgery and in motility disorders. These alterations underlie conditions such as ileus, pseudo‐obstruction, and fecal incontinence, and may be modulated by sacral neuromodulation.
Penfold JA +3 more
europepmc +2 more sources
Regenerative Therapy, 2021 Introduction: Low anterior resection syndrome (LARS) is the most common complication after total mesorectal excision (TME) in patients with low rectal cancer and has been a challenge in colorectal surgery that severely impacts the quality of life of ...
Haiquan Qin +8 more
doaj +1 more source
Risk factors of the low anterior resection syndrome (LARS) after ileostomy reversal in rectal cancer patient. [PDF]
Sci RepThis study is aimed at identifying risk factors of Low Anterior Resection Syndrome following ileostomy reversal in rectal cancer patients who had undergone preventive ileostomy. This retrospective analysis was conducted on a cohort of 605 patients treated at the Fourth Hospital of Hebei Medical University between January 2018 and December 2021.
Zhang X +6 more
europepmc +4 more sources
The Effect of Anastomotic Leakage on the Incidence and Severity of Low Anterior Resection Syndrome in Patients Undergoing Proctectomy: A Propensity Score Matching Analysis [PDF]
Annals of Coloproctology, 2021 Purpose Proctectomy for the treatment of rectal cancer results in inevitable changes to bowel habits. Symptoms such as fecal incontinence, constipation, and tenesmus are collectively referred to as low anterior resection syndrome (LARS).
Sungjin Kim +3 more
doaj +1 more source
Journal of Investigative Surgery, 2022 Background: There is a relative shortage of studies directly addressing the postoperative rectal cancer patients’ evacuatory dysfunction, as estimated by the low anterior resection syndrome (LARS) score at repeated assessment time-points.
George E. Theodoropoulos +5 more
doaj +1 more source
LARS is Associated with Lower Anastomoses, but not with the Transanal Approach in Patients Undergoing Rectal Cancer Resection. [PDF]
, 2021 BACKGROUND Low anterior resection syndrome (LARS) is a defecation disorder that frequently occurs after a low anterior resection (LAR) with a total mesorectal excision (TME). The transanal (ta) TME for low rectal pathologies could potentially overcome
Brügger, Lukas +5 more
core +1 more source
Low anterior resection syndrome (LARS) and quality of life after colectomy
International Journal of Colorectal Disease, 2023 Clinical experience shows complaints similar to LARS not only after rectal surgery, but even after other types of colorectal surgery. Our aim was to investigate the occurrence of LARS after several types of colorectal surgery and its impact on quality of life.We included adult patients who underwent colorectal surgery at our centre from January 2016 ...
Juul Meurs +5 more
openaire +3 more sources