Distinct trajectories of low anterior resection syndrome following ileostomy reversal [PDF]
Frontiers in MedicinePurposeThis study is an midterm postoperative assessment of LARS symptoms, aiming to apply group-based trajectory modeling to analyze the symptom trajectories of low anterior resection syndrome in rectal cancer patients who underwent ileostomy and ...
Xuena Zhang +7 more
doaj +2 more sources
Factors determining low anterior resection syndrome after rectal cancer resection: A study in Thai patients [PDF]
Asian Journal of Surgery, 2016 Background/Objective: Defective defecation function, also known as low anterior resection syndrome (LARS), is a common problem after surgical treatment of rectal cancer that has a detrimental effect on quality of life.
Patomphon Ekkarat +3 more
doaj +2 more sources
Is transanal irrigation the best treatment possibility for low anterior resection syndrome? A multicenter, randomized clinical trial: study protocol [PDF]
Frontiers in SurgeryBackgroundUp to 50% of patients who undergo rectal resection suffer from various and partly severe functional problems, despite the preservation of the anal sphincter. These complaints are defined as low anterior resection syndrome (LARS).
Michail Klimovskij +8 more
doaj +2 more sources
Low anterior resection syndrome after rectal cancer surgery: mechanisms, assessment, management, and the potential role of robotic surgery [PDF]
Frontiers in OncologyRectal cancer is one of the most commonly diagnosed malignancies in the digestive system. In recent years, with continuous advances in systemic therapies such as chemotherapy and radiotherapy, as well as the widespread implementation of the ...
Chenyu Zhang +4 more
doaj +2 more sources
Cancer Management and ResearchWaheeb Radman Al-Kubati1– 3 1Department of Surgery, 21st September University, Sana’a, Yemen; 2Department of Surgery, Althowra Modern General Hospital, Sana’a, Yemen; 3Department of Physiology, Sana’a University, Sana’a, YemenCorrespondence: Waheeb ...
Al-Kubati WR
doaj +1 more source
Association between pre-reversal systemic inflammation response index and low anterior resection syndrome in rectal cancer patients: a retrospective cohort study [PDF]
Frontiers in OncologyPurposeThis study aims to explore the relationship between the systemic inflammation response index (SIRI) and the development of low anterior resection syndrome (LARS) in rectal cancer patients after ileostomy closure.MethodsThis retrospective cohort ...
Xuena Zhang +7 more
doaj +2 more sources
Reconsidering the LARS score: a cross-sectional descriptive study exploring complementary screening approaches for low anterior resection syndrome. [PDF]
Int J Colorectal DisAbstract Purpose The LARS score is a practical tool to screen for bowel dysfunction after rectal cancer surgery. However, clinical experience suggests that it may overlook relevant symptoms and/or overestimate impact in some patients.
Ribas Y +6 more
europepmc +4 more sources
The role of colonic motility in low anterior resection syndrome
Frontiers in Oncology, 2022 Low anterior resection syndrome (LARS) describes the symptoms and experiences of bowel dysfunction experienced by patients after rectal cancer surgery.
Chris Varghese +7 more
doaj +1 more source
Frontiers in Surgery, 2022 BackgroundThe low anterior resection syndrome (LARS) score is a validated questionnaire developed in Denmark to measure the severity of bowel dysfunction after low anterior resection. This retrospective study aimed to assess the effectiveness of the LARS
Veronica De Simone +13 more
doaj +1 more source
Hepatology, EarlyView., 2022 Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.
Shannon M. Vandriel +93 more
wiley +1 more source