Score assessment and treatment in patients presenting with low anterior resection syndrome after sphincter-sparing rectal cancer surgery. [PDF]
Sphincter-sparing low anterior resection (SSLAR) with neoadjuvant radio-chemotherapy has been developed to avoid abdomino-perineal amputation and permanent colostomy in patients with low rectal cancer. However, many patients develop symptoms known as low
Sguinzi R +7 more
europepmc +2 more sources
Optimal interventions for low anterior resection syndrome: Bayesian network meta-analysis of randomized controlled trials. [PDF]
The optimal intervention for managing low anterior resection syndrome (LARS) remains uncertain. This Bayesian network meta-analysis was conducted to compare and rank the effectiveness of various interventions on LARS.
Yu M +7 more
europepmc +2 more sources
Understanding risk factors for low anterior resection syndrome in a South American cohort. [PDF]
Background: Low Anterior Resection Syndrome (LARS) is a common postoperative bowel dysfunction in patients undergoing sphincter-preserving surgery for rectal cancer.
Gaete MI +4 more
europepmc +2 more sources
Effect of psyllium husk on low anterior resection syndrome after rectal cancer surgery-a pilot prospective cohort study. [PDF]
Introduction Low anterior resection syndrome (LARS) is a frequent, undesired consequence of rectal cancer surgery. Psyllium husk has been suggested as a nutritional supplement in the management of LARS, but without trial-based evidence of its effect.
Holte SS +6 more
europepmc +2 more sources
The Role of Patient Education in Low Anterior Resection Syndrome: A Systematic Review. [PDF]
Low anterior resection syndrome (LARS) is a significant complication after sphincter-preserving rectal cancer surgery and negatively impacts a patient’s quality of life.
Tang P +8 more
europepmc +2 more sources
Advanced Reconstructive Techniques: Mitigating Low Anterior Resection Syndrome Post-TME in Low Rectal Cancer - A Single-Center Randomised Controlled Study. [PDF]
Background Low Anterior Resection Syndrome (LARS) is a debilitating complication of sphincter-preserving surgeries, particularly after Total Mesorectal Excision (TME) for very low rectal cancer.
Al-Kubati WR.
europepmc +2 more sources
The impact of Low-Anterior Resection Syndrome (LARS) on the Quality of Life in Rectal Cancer Survivors: a Narrative Review. [PDF]
Low anterior rectal cancer is based on oncological radicality and recurrence rates, which translate to survival. Rectal dysfunction occurred in at least one-quarter of patients.
Stanculea F +6 more
europepmc +2 more sources
Long-term outcomes of transanal irrigation in patients with low anterior resection syndrome: what happens after more than five years? [PDF]
Low anterior resection syndrome (LARS) significantly impacts quality of life after rectal cancer surgery. Transanal irrigation (TAI) is a potential treatment, but long-term outcome data are limited.
Martellucci J +5 more
europepmc +2 more sources
A systematic review of preoperative radiological factors associated with the development of low anterior resection syndrome (LARS). [PDF]
The aim of this systematic review is to summarise the available evidence for radiological changes associated with postoperative low anterior resection syndrome (LARS).
Gravante G +3 more
europepmc +2 more sources
Effects of low anterior resection syndrome after colorectal cancer resections on health-related quality of life: a systematic review and meta-analysis. [PDF]
Low anterior resection syndrome (LARS) is a term that encompasses multidimensional bowel dysfunction that typically occurs following resections of rectum and distal parts of the colon.
Shojaei-Zarghani S +4 more
europepmc +2 more sources

