Results 51 to 60 of about 23,670 (281)

Transverse coloplasty pouch and colonic J-pouch for rectal cancer: a comparative study [PDF]

open access: yes, 2003
OBJECTIVES: The introduction of the colonic J-pouch has markedly improved the functional outcome of restorative rectal cancer surgery. However colonic J-pouch surgery can be problematic and may present some late evacuatory problems.
Duarte, A   +4 more
core   +1 more source

The Fate (Outcome) of Clinically Apparent Single Lesion and Oligofocal Nephroblastomatosis Treated According to SIOP/GPOH Protocols for Wilms Tumor

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter   +17 more
wiley   +1 more source

High and low inferior mesenteric artery ligation in laparoscopic low anterior rectal resections: A retrospective study

open access: yesFrontiers in Surgery, 2023
BackgroudThe high or low inferior mesenteric artery (IMA) ligation in rectal cancer remains a great debate. This study retrospectively discussed the outcomes of the perioperative period, defecation and urinary function and long-term prognosis in rectal ...
Jun Yu   +8 more
doaj   +1 more source

Patterns of injury and violence in Yaoundé Cameroon: an analysis of hospital data. [PDF]

open access: yes, 2010
BackgroundInjuries are quickly becoming a leading cause of death globally, disproportionately affecting sub-Saharan Africa, where reports on the epidemiology of injuries are extremely limited.
Bilounga Ndongo, Chancelline   +4 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Incidence of the anterior resection syndrome using low anterior resection score (LARS scale)

open access: yes, 2017
Background Up to 90 % of patients undergoing low anterior resection, complain of increased daily bowel movements, urgency for defecation, and a variable degree of incontinence. A symptom-based scoring system for bowel dysfunction after low anterior resection for rectal cancer has recently been validated in Lithuanian population.
Dulskas, Audrius   +4 more
openaire   +1 more source

Investigation of knowledge, attitudes and practices regarding prevention of low anterior resection syndrome in rectal cancer patients with prophylactic stoma: a multicenter cross-sectional study

open access: yes结直肠肛门外科
[Objectives] To investigate the current status of knowledge, attitudes and practices regarding prevention of low anterior resection syndrome in rectal cancer patients with prophylactic stoma and analyze influencing factors.
Liu Na   +3 more
doaj   +1 more source

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

open access: yesAdvanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu   +16 more
wiley   +1 more source

Identifying quantitative imaging features of posterior fossa syndrome in longitudinal MRI [PDF]

open access: yes, 2015
Up to 25% of children who undergo brain tumor resection surgery in the posterior fossa develop posterior fossa syndrome (PFS). This syndrome is characterized by mutism and disturbance in speech.
Avula, Shivaram   +4 more
core   +1 more source

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