Results 171 to 180 of about 388,166 (298)

Deciphering and Targeting the Schwannoma‐Neuron‐Macrophage Crosstalk for the Treatment of Schwannomatosis and Associated Pain

Advanced Science, EarlyView.
We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin, Limeng Wu, Yanling Zhang, Yao Sun, Grace Y. Lee, Simeng Lu, Xing Gao, John W. Chen, Sonu Subudhi, William Ho, Chao Zhu, Jun Ren, Gino B. Ferraro, Alona Muzikansky, Anat Stemmer‐Rachamimov, Jianren Mao, Scott R. Plotkin, Lei Xu   +17 more
wiley   +1 more source

Effectiveness of epidural steroid injections for low back pain in older adults: a systematic review. [PDF]

Aging Clin Exp Res
Zhu AC, Mysior CR, LaRowe LR, Abadir PM, Haines L, Chan J, Aslakson RA.   +6 more
europepmc   +1 more source

Effects of Pelvic Mobility Exercise Combined with Dynamic Taping on Lumboscaral Angle and Pelvic Tilt in Patients with Low Back Pain

Taeyun Kim, Sang Ho Lee, Woo Nam Chang
openalex   +1 more source

Gambaran Low Back Pain pada Karyawan Petugas Tol di PT X Periode 2014 -2017

, 2019
Albert Arifin, Judin Purba Tanjung, Budiman Hartono   +2 more
openalex   +2 more sources

Ultrasound Modulation of Visual Circuits in Mice Independent of Auditory Confound

Advanced Science, EarlyView.
In this study, Qiu et al. found that low‐intensity ultrasound can directly activate sparse ultrasound‐sensitive neurons (UNs) in the primary visual cortex (V1) of deafened mice. The proportion of these sparse UNs is pressure‐dependent. Furthermore, ultrasound modulates visual circuitry with distinct excitatory and inhibitory effects.
Jiaru He, Jiejun Zhu, Xinxin Wang, Zihao Chen, Jin Yang, Zhen Yuan, Hongzhi Xu, Lei Sun, Zhihai Qiu   +8 more
wiley   +1 more source

Bioengineering Innovations for Personalized Care in Low Back Pain: From Sensors to Smart Therapeutics. [PDF]

Bioengineering (Basel)
Gallo J, Stefancik M, Mik P, Lhotska L.
europepmc   +1 more source

A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia

Advanced Science, EarlyView.
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun, Jia‐Jia Wang, Xiang‐Yu Li, Xin‐Yi Lin, Juan Li, Qiu‐Tong Yu, Zi‐Han Wang, Xue‐Ping Gao, Lei Jin, Wei‐Ke Li, Tian‐Lin Cheng, Juan Deng   +11 more
wiley   +1 more source

Comparative effectiveness of amitriptyline <i>vs</i> duloxetine in the treatment of chronic low back pain: An observational study. [PDF]

World J Methodol
Sardar N, Swarnakar R, Ghosh S, Mandal PK.   +3 more
europepmc   +1 more source

Proper manual handling techniques to prevent low back pain, a Cochrane Systematic Review

, 2012
Jos Verbeek, Kari-Pekka Martimo, Paul Kuijer, Jaro Karppinen, Eira Viikari‐Juntura, Esa‐Pekka Takala   +5 more
openalex   +2 more sources

Developmentally Inspired, Mechanical–Metabolic Dual Gradient Osteochondral Constructs Bridging Regeneration and Therapeutic Screening

Advanced Science, EarlyView.
A developmentally inspired osteochondral construct integrates mechanical and metabolic dual gradients within a 3D‐printed platform. Human MSC spheroids are spatially directed to form cartilage–bone interfaces, enabling evaluation of regeneration without biochemical reagents and assessment of drug responses. This physiologically relevant, phase‐specific
Yurim Choi, Wonjun Jang, Raehui Kang, Ulziituya Batjargal, Jihyeon Song, Soojin Park, MinSeok Kim, Hyobum Cho, Junhyung Kim, Yu Shrike Zhang, Han‐Jun Kim, Junmin Lee   +11 more
wiley   +1 more source