Results 31 to 40 of about 11,908,083 (267)

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Type 2 Diabetes Risk Alleles Are Associated With Reduced Size at Birth [PDF]

, 2009
OBJECTIVE: Low birth weight is associated with an increased risk of type 2 diabetes. The mechanisms underlying this association are unknown and may represent intrauterine programming or two phenotypes of one genotype.
Timpson, NJ, Ruokonen, A, Weedon, Michael N, Hattersley, AT, McCarthy, MI, Pouta, Anneli, Lindgren, Cecilia M, Perry, JR, Weedon, MN, Elliott, P, Groves, Christopher J, Smith, GD, Shields, B, Power, C, Järvelin, MR, Hyppönen, E, Shields, Beverley, Zeggini, Eleftheria, McCarthy, Mark I, Bennett, Amanda J, Ring, Susan M, Power, Chris, Ring, SM, Ruokonen, Aimo, Pouta, A, Strachan, DP, Elliott, Paul, Järvelin, Marjo-Riitta, Timpson, Nicholas J, Lango, Hana, Groves, CJ, Bennett, AJ, Hattersley, Andrew T, Lindgren, CM, Smith, George Davey, Zeggini, E, Frayling, Timothy M, Strachan, David P, Lango, H, Hyppönen, Elina, Freathy, RM, Perry, John R B, Frayling, TM, Freathy, Rachel M, Freathy, R.M., Hypponen, E., Hattersley, A.T., Shields, B., Ring, S.M., Bennett, A.J.   +49 more
core   +1 more source

Changing trends of birth weight with maternal age: a cross-sectional study in Xi’an city of Northwestern China

BMC Pregnancy and Childbirth, 2020
Background Most studies have shown that maternal age is associated with birth weight. However, the specific relationship between each additional year of maternal age and birth weight remains unclear.
Shanshan Wang, Liren Yang, Li Shang, Wenfang Yang, Cuifang Qi, Liyan Huang, Guilan Xie, Ruiqi Wang, Mei Chun Chung   +8 more
doaj   +1 more source

Effect of Gestational Weight Gain on Associations Between Maternal Thyroid Hormones and Birth Outcomes

Frontiers in Endocrinology, 2020
Purpose: The aim was to investigate the associations between maternal thyroid parameters within the normal ranges during early pregnancy and birth outcomes, and further to examine whether the associations were modified by gestational weight gain (GWG ...
Bin Zhou, Yao Chen, Wen-Qian Cai, Ling Liu, Xi-Jiang Hu   +4 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Genetic variation in the 15q25 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) interacts with maternal self-reported smoking status during pregnancy to influence birth weight [PDF]

, 2012
Maternal smoking during pregnancy is associated with low birth weight. Common variation at rs1051730 is robustly associated with smoking quantity and was recently shown to influence smoking cessation during pregnancy, but its influence on birth weight is
Paternoster, Lavinia, Freathy, R.M., Ng, J.W.Y., Johnson, P.C.D., Watt, GCM, Ebrahim, S, Potter, C, Hartikainen, A.L., Lowe, William L., Potter, C. (Catherine), Johnson, PC, Watt, GC, Ng, JWY, Ebrahim, Shah, Taal, H.R., Christie, J.D. (Jason), Lowe Jr., W.L. (William), Johnson, P., Hattersley, Andrew T., Watt, G.C.M., Brion, M.-J.A., Kaakinen, M, Brion, M.-J. (Maria), Sorensen, T.I.A., Geller, F. (Frank), Sørensen, Thorkild IA, Ng, Jane WY, Cavadino, Alana, Kaakinen, Marika, Freathy, RM, Myhre, R. (Ronny), Johnson, Paul CD, Freathy, R.M. (Rachel), Lowe, LP, Hofman, Bert, Johnson, Paul C D, Brion, MJ, Sengpiel, V. (Verena), Hypponen, Elina, Davey Smith, George, Cavadino, A, Huikari, V, Ebrahim, S., Hartikainen, A., Frayling, Timothy M., Taal, HR, Sebert, SP, Lawlor, D.A. (Debbie), Murray, J.C., Huikari, V. (Ville), Lowe, L., Hofman, A., Brion, M., Sattar, Naveed, Jaddoe, Vincent W. V., Hartikainen, Anna-Liisa, Johnson, P.C.D. (Paul C.), Jarvelin, Marjo-Riitta, Hartikainen, AL, Bakker, R, Nohr, EA, Murray, J.C. (Jeffrey), Paternoster, L., Sattar, N, Lowe, L.P. (Lynn), Pennell, C.E., Smith, GD, Smith, G. D., Jacobsson, Bo, Power, C., Hattersley, A.T., Magnus, P, Sengpiel, Verena,, Magnus, Per,, Sorensen, Thorkild, Jarvelin, M.-R. (Marjo-Riitta), ?, ?, Lawlor, DA, Melbye, M. (Mads), Relton, C.L., et al., Lawlor, D.A., Pennell, Craig E., Jacobsson, B., Christie, Jennifer T, Myhre, R, Power, Chris, Ring, Susan M, McConnachie, A. (Alex), Davey Smith, G, Melbye, Mads, Pennell, C.E. (Craig), Relton, Caroline L., Jaddoe, Vincent W V, Sørensen, TIA, Lawlor, Debbie A., Freathy, Rachel M., Frayling, Timothy M, Watt, Graham C M, Jaddoe, VW, Srensen, TIA, Jaddoe, VWV, Jacobsson, B. (Bo), Cavadino, A., Pennell, CE, Jacobsson, Bo,, Cavadino, A. (Alana), Pennell, Craig E, Hartikainen, A.-L., Relton, Caroline L, Early Growth Genetics (EGG) Consortium, Lowe, WL, Ring, SM, Lowe, Lynn P., Feenstra, B, Sattar, N. (Naveed), Potter, C., Feenstra, B., McConnachie, A, Hattersley, Andrew T, Hattersley, A.T. (Andrew), Sengpiel, V., Smith, George Davey, Nohr, E.A., Feenstra, B. (Bjarke), Ng, J.W. (Jane), Watt, G.C. (Graham), Srensen, Thorkild IA, Ring, S.M., Freathy, Rachel M, Sengpiel, V, Hofman, A. (Albert), Hattersley, AT, Sebert, S.P., Kaakinen, M., Geller, F, Nohr, C. (Christian), Sattar, N., Sengpiel, Verena, Jaddoe, Vincent WV, Huikari, Ville, Power, C, Tyrrell, Jessica, Lawlor, Debbie A, Feenstra, Bjarke, Lowe, Lynn P, Jacobsson, B, Taal, Rob; id_orcid, Sørensen, T.I.A. (Thorkild), Paternoster, L. (Lavinia), Jaddoe, V.W.V. (Vincent), Brion, Marie-Jo A, Frayling, T.M. (Timothy), Hypponen, E. (Elina), Hattersley, A., Brion, MJA, Relton, CL, Christie, Jennifer T., Sebert, Sylvain P., Jaddoe, Vincent, Johnson, PCD, Frayling, TM, Christie, JT, Murray, JC, Johnson, Paul C. D., Tyrrell, A.W.R., Jaddoe, V.W.V., Jarvelin, MR, Magnus, P. (Per), Myhre, Ronny, Power, C. (Christopher), Sørensen, TI, Lowe, William L, Geller, Frank, Murray, Jeffrey C., Bakker, R., Jarvelin, M.-R., Hypponen, E., Taal, H Rob, Relton, C.L. (Caroline), McConnachie, A., Nohr, Ellen A, Christie, J., Murray, Jeffrey C, Nohr, Ellen A., McConnachie, Alex, Christie, J.T., Hofman, A, Bakker, R. (Rachel), Frayling, T.M., Watt, Graham C. M., Hypponen, E, Melbye, M, Ng, JW, Smith, A.V. (Davey), Taal, H. Rob, Hofman, Albert, Ring, S.M. (Susan), Huikari, V., Ring, Susan M., Sebert, Sylvain P, Tyrrell, J, Taal, H.R. (Rob), Magnus, P., Lowe, L.P., Lowe, W. L., Ng, Jane W. Y., Tyrrell, J., Ebrahim, S. (Shanil), Sørensen, Thorkild I A, Myhre, R., Magnus, Per, Sebert, S. (Sylvain), Kaakinen, M. (Marika), Bakker, Rachel, Ng, Jane W Y, Geller, F., Potter, Catherine, Paternoster, L, Melbye, M., Watt, Graham CM, Brion, Marie-Jo A., Srensen, Thorkild I. A., Lowe, William L., Jr.   +223 more
core   +1 more source

Pattern and Determinants of Birth Weight in a Rural Popula-tion of Punjab, India

National Journal of Community Medicine, 2017
Introduction: Birth weight is a strong predictor for ensuring healthy life of a newborn and is affected by various maternal and social determinants.
Mahesh Satija, Vikram Kumar Gupta, Anurag Chaudhary, Sarit Sharma, Sangeeta Girdhar, Surinderpal Singh   +5 more
doaj  

Factors associated with weight Z-score in very low birth weight and extremely low birth weight preterm infants during hospitalization

Jornal de Pediatria
Objective: To investigate the behavior of weight-for-age z-score (WAZ) and associated factors in preterm newborns (PTNB) with very low birth weight (VLBW) and extremely low birth weight (ELBW), comparing them to low birth weight (LBW) during four weeks ...
Eduarda Couto Plácido Nunes, Eduarda Silva, Eduarda Dallmann Lopes Pereira, Karla Pereira Machado, Sandra Costa Valle   +4 more
doaj   +1 more source