Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Birth weight and cognitive function in the British 1946 birth cohort: longitudinal population based study [PDF]
, 2001 Objective To examine the association between birth weight and cognitive function in the normal population.Design A longitudinal, population based, birth cohort study.Participants 3900 males and females born in 1946.Main outcome measures Cognitive ...
Richards, M +3 more
core
Can mothers judge the size of their newborn? Assessing the determinants of a mother's perception of a baby's size at birth [PDF]
, 2011 Birth weight is known to be closely related to child health, although as many infants in developing countries are not weighed at birth and thus will not have a recorded birth weight it is difficult to use birth weight when analysing child illness.
Channon, Andrew, ANDREW A. R. CHANNON
core +1 more source
Low birth weight and its association factors in Iran: according world health organization model
Journal of Rehabilitation, 2012 Objective: Birth weight is one of the most important ,simplest and common determinations for assessments infants status in each country. this study has been designed to investigate the articles that published in its prevalence and related factors ...
zohreh Mahmoudi +4 more
doaj
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Low birth weight and birth weight status in Bangladesh: A systematic review and meta-analysis
Anthropological Review, 2021 The prevalence of low birth weight (LBW) is high in Bangladesh, but no study has collated recent estimates of LBW prevalence from throughout the country.
Shaikh Saijuddin +2 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Low birth weight for gestation and airway function in infancy: exploring the fetal origins hypothesis [PDF]
, 2004 Background: Poor fetal growth has been associated with impaired airway function in adult life, but evidence linking birth weight and airway function in early childhood is sparse.
Lum, S +5 more
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Effect of enteral glutamine supplementation for low-birth-weight infants on weight gain patterns and levels of fecal secretory immunoglobulin A [PDF]
, 2018 Aim: Glutamine is needed for optimal cell growth and for the immune system, especially in the enterocytes of gut mucosal immune responses. Low birth weight makes infants susceptible to glutamine depletion because nutrition is limited in the first week of
Martono Tri Utomo, - +15 more
core +1 more source