Results 41 to 50 of about 1,136,223 (342)

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Distribution and Determinants of Low Birth Weight in Developing Countries

Journal of preventive medicine and public health = Yebang Uihakhoe chi, 2016
Objectives Low birth weight (LBW) is a major public health concern, especially in developing countries, and is frequently related to child morbidity and mortality.
R. Mahumud, M. Sultana, A. Sarker
semanticscholar   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Changing trends of birth weight with maternal age: a cross-sectional study in Xi’an city of Northwestern China

BMC Pregnancy and Childbirth, 2020
Background Most studies have shown that maternal age is associated with birth weight. However, the specific relationship between each additional year of maternal age and birth weight remains unclear.
Shanshan Wang, Liren Yang, Li Shang, Wenfang Yang, Cuifang Qi, Liyan Huang, Guilan Xie, Ruiqi Wang, Mei Chun Chung   +8 more
doaj   +1 more source

Effect of Gestational Weight Gain on Associations Between Maternal Thyroid Hormones and Birth Outcomes

Frontiers in Endocrinology, 2020
Purpose: The aim was to investigate the associations between maternal thyroid parameters within the normal ranges during early pregnancy and birth outcomes, and further to examine whether the associations were modified by gestational weight gain (GWG ...
Bin Zhou, Yao Chen, Wen-Qian Cai, Ling Liu, Xi-Jiang Hu   +4 more
doaj   +1 more source

Maternal Anemia during pregnancy and infant low birth weight: A systematic review and Meta-analysis

International Journal of Reproductive BioMedicine, 2017
Background: Infant low birth weight is one of the major problems in different societies. Different reports have provided different results regarding the relationship between maternal anemia and infant low birth weight in different months of pregnancy ...
S. Rahmati, A. Delpishe, M. Azami, Mohammed Reza Hafezi Ahmadi, K. Sayehmiri   +4 more
semanticscholar   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Renal repercussion of low birth weight

Revista Habanera de Ciencias Médicas, 2023
Introduction: Developmental programming predisposes the individual to suffer from diseases during adulthood. Low birth weight (LBW) is one of the markers of the adverse intrauterine environment.
Adina Pérez Mejías, Mailin Claxton Louit, Melvis Taylín Zumeta Dubé   +2 more
doaj  

Low birth weight leads to obesity, diabetes and increased leptin levels in adults: the CoLaus study

Cardiovascular Diabetology, 2016
BackgroundLow birth weight is associated with increased rates of obesity, insulin resistance and type 2 diabetes, but the precise mechanisms for this association remain unclear.
F. Jornayvaz, P. Vollenweider, M. Bochud, V. Mooser, G. Waeber, P. Marques-Vidal   +5 more
semanticscholar   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source